Original Articles: Drug Allergy, Insect Sting Allergy, and Anaphylaxis
Drug allergies, insect sting allergies, and anaphylaxis are severe
allergic reactions that pose significant health risks worldwide.
Drug allergies occur when the immune system reacts adversely to
medications, leading to symptoms ranging from mild rashes to
life-threatening anaphylaxis. Common culprits include antibiotics,
nonsteroidal anti-inflammatory drugs (NSAIDs), and chemotherapy
agents. Insect sting allergies, triggered by the venom of bees,
wasps, hornets, or ants, can also result in severe reactions and
anaphylaxis, characterized by difficulty breathing, swelling, and a
sudden drop in blood pressure.
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62 Articles |
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Deciphering Immune Endotypes Within Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome
C. von Wachter, M. Ameri, T. Chimbetete, et al. Allergy. First published: 23 June 2025
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Direct Single-Dose Drug-Provocation Test Is Safe for Delabelling Penicillin Low-Risk Reactions in Adults
Labella, M., Rodriguez de Guzmán, J., Diez-Echave, P., et al. Allergy. First published:16 May 2025
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The Discrepancy Between Perceived and Proven Drug Hypersensitivity in a Well-Defined Cohort of Patients With Inborn Errors of Immunity
Bilgic-Eltan, S., Karakurt, T., Yuksel, R.G., et al.Allergy. First published:29 April 2025
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Targeting the Galectin-7/TRPM2/Zn2+/DRP-1 Signaling Pathway: A Potential Therapeutic Intervention in the Pathogenesis of SJS/TEN
Zhang, C., Pang, B., Luo, Y., et al. Allergy. First published: 05 March 2025
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Discrepancies in Beta-Lactam Antibiotics Cross-Reactivity: Implications for Clinical Practice
Hutten, E.M., Bulatović Ćalasan, M., Trubiano, J.A., et al. Allergy. First published: 21 February 2025
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Basophil Activation Test Positivity Decreases With Time in Immediate Allergic Reactions to Proton Pump Inhibitors
Fernandez-Santamaria, R., Salas, M., Ariza, A., et al. Allergy. First published: 27 November 2024
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Feedback regulation of VISTA and Treg by TNF-α controls T cell responses in drug allergy
Sun L, Zhao Q, Ao S, et al. Allergy. First published: 11 November 2024
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Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes
Bogas G, Ariza A, Vázquez-Revuelta P, et al. Allergy. First published: 31 August 2024
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Aspirin hypersensitivity diagnostic index (AHDI): In vitro test for diagnosing of N-ERD based on urinary 15-oxo-ETE and LTE4 excretion
Mastalerz L, Trąd G, Szatkowski P, et al. Allergy. First published: 23 August 2024
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Impact of a drug allergy education course for non-specialists: Findings from ADAPT—A randomized crossover trial
Lucas M, Mak HWF, Lee JTY, Kulkarni R, Chan SSC, Li PH. Allergy. First published: 07 August 2024
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Prevalence of hypersensitivity reactions in various forms of mastocytosis: A pilot study of 2485 adult patients with mastocytosis collected in the ECNM registry
Niedoszytko M, Gorska A, Brockow K, et al. Allergy. First published: 23 April 2024
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High burden of clonal mast cell disorders and hereditary α-tryptasemia in patients who need Hymenoptera venom immunotherapy
Korošec P, Sturm GJ, Lyons JJ, et al. Allergy. First published: 13 March 2024
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Global burden of vaccine-associated anaphylaxis and their related vaccines, 1967–2023: A comprehensive analysis of the international pharmacovigilance database
Lee K, Lee H, Kwon R, et al. Allergy. First published: 10 December 2023
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Differential presentation of hypersensitivity reactions to carboplatin and oxaliplatin: Phenotypes, endotypes, and management with desensitization
Jimenez-Rodriguez T-W, de las Vecillas L, Labella M, et al. Allergy. First published: 02 November 2023
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Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-Desmethyl Naproxen metabolite but not the acyl glucuronide
Thomson, P, Fragkas, N, Kafu, LM, et al. Allergy. First published: 29 July 2023
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The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naïve healthy donors
Mifsud, NA, Illing, PT, Ho, R, et al. Allergy. First published: 14 July 2023
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Oral prednisone regulates human skin T cells in delayed-type hypersensitivity reaction elicited by diphencyprone
Mehta, H., Jack, C., Maari, C., et al. Allergy. First published: 10 May 2023
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Optimal dose of adrenaline auto-injector for children and young people at risk of anaphylaxis: A phase IV randomized controlled crossover study
Patel, N, Isaacs, E, Duca, B, et al. Allergy. First published: 16 February 2023
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Fatal and near-fatal anaphylaxis: the Allergy-Vigilance® Network data (2002-2020)
Pouessel, G., Alonzo, S., Divaret-Chauveau, A., Dumond, P., et al. Allergy. First published: 16 January 2023
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Different phenotypes of drug-induced anaphylaxis - data from the European Anaphylaxis Registry
Hanschmann, T., Francuzik, W., Dölle-Bierke, S., et al. Allergy. First published: 08 December 2022
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Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study
Céspedes, J.A., Fernández-Santamaría, R., Ariza, A., et al. Allergy. First published: 07 December 2022
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Intravenous immunoglobulins, cyclosporine and best supportive care in Epidermal Necrolysis: Diverse effects on systemic inflammation
Schmidt, V., Lalevée, S., Traidl, S., et al. Allergy. First published: 04 December 2022
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Diagnostic value of a medical algorithm for investigation of perioperative hypersensitivity reactions
Sverrild, A., Carruthers, J., Murthee, K.G., et al. Allergy. First published: 22 September 2022
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Resensitisation in suspected penicillin allergy
Doña, I., Guidolin, L., Bogas, G., et al. Allergy. First published: 06 September 2022
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Personalized diagnostic approach and indirect quantification of extravasation in human anaphylaxis
Nuñez-Borque, E., Betancor, D., Carlos, P.-V., et al. Allergy. First published: 16 July 2022
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Management of suspected and confirmed COVID-19 (SARS-CoV-2) vaccine hypersensitivity
Worm, M., Alexiou, A., Bauer, A., et al. Allergy. First published: 20 June 2022
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Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions
Fernandez-Santamaria, R, Bogas, G, Montañez, MI, et al. Allergy. First published: 24 May 2022
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IgE antibodies increase honeybee venom responsiveness and detoxification efficiency of mast cells
Starkl, P., Gaudenzio, N., Marichal, T., et al. Allergy. First published: 11 April 2021
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Platelet-activating factor acetylhydrolase is a biomarker of severe anaphylaxis in children
Upton, J.E.M., Hoang, J.A., Leon-Ponte, M.,et al. Allergy. First published: 09 April 2022
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Experience with polyethylene glycol allergy-guided risk management for COVID-19 vaccine anaphylaxis
Brockow, K, Mathes, S, Fischer, J, et al. et al. Allergy. First published: 22 November 2021
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The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine
Labella, M., Céspedes, J.A., Doña, I., et al. Allergy. First published: 24 October 2021
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Next-generation sequencing and genotype association studies reveal the association of HLA-DRB3*02:02 with delayed hypersensitivity to penicillins
Romano, A., Oussalah, A., Chery, C., et al. Allergy. First published: 23 October 2021
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Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients
Mitamura, Y., Schulz, D., Oro, S., et al. Allergy. First published:22 June 2021
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IgE-cross-blocking antibodies to Fagales following sublingual immunotherapy with recombinant Bet v 1
Grilo, J.R., Kitzmüller, C., Aglas, L., et al. Allergy. First published: 16 March 2021
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Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy
Tesfaye, A., Rodríguez-Nogales, A., Benedé, S., et al. Allergy. 2021; 76: 3183-3193
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Single-dose prolonged drug provocation test, without previous skin testing, is safe for diagnosing children with mild non-immediate reactions to beta-lactams
Prieto, A., Muñoz, C., Bogas, G., et al. Allergy.2021; 76: 2544-2554
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Childhood vaccination and allergy: A systematic review and meta-analysis
Navaratna, S., Estcourt, M.J., Burgess, J., et al. Allergy.2021; 76: 2135-2152
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Dendritic cells inclusion and cell-subset assessment improve flow-cytometry-based proliferation test in non-immediate drug hypersensitivity reactions
Fernandez-Santamaria, R., Bogas, G., Palomares, F., et al. Allergy.2021; 76: 2123-2134
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Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat
Thomson, PJ, Kafu, L, Meng, X, et al. Allergy. 2021; 76: 1825– 1835
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Digital technology for anaphylaxis management impact on patient behaviour: A randomized clinical trial
Sala-Cunill, A, Luengo, O, Curran, A, et al. Allergy. 2021; 76: 1507– 1516
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Diagnosing, managing and preventing anaphylaxis: Systematic review
de Silva, D, Singh, C, Muraro, A, et al. Allergy. 2021; 76: 1493– 1506
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Food-dependent NSAID-induced hypersensitivity (FDNIH) reactions: Unraveling the clinical features and risk factors
Sánchez-López, J, Araujo, G, Cardona, V, et al. Allergy. 2021; 76: 1480– 1492
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Diagnostic workup including CD203c-based basophil activation test in immediate hypersensitivity due to metronidazole and ornidazole and evaluation of cross-reactivity in between
Beyaz, Ş, Akdeniz, N, Yılmaz, A, et al. Allergy. 2021; 76: 842– 852
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IgE-mediated chlorhexidine allergy—Cross-reactivity with other biguanide disinfectants
Mueller-Wirth, N, Buenter, A, Jörg, L, et al. Allergy. 2020; 75: 3237– 3247
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Fatal anaphylaxis in Italy: Analysis of cause-of-death national data, 2004-2016
Bilò, MB, Corsi, A, Martini, M, Penza, E, Grippo, F, Bignardi, D. llergy. 2020; 75: 2644– 2652
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Characterization of amoxicillin and clavulanic acid specific T-cell clones from patients with immediate drug hypersensitivity
Ariza, A, Fernández-Santamaría, R, Meng, X, et al. Allergy. 2020; 75: 2562– 2573
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Artificial neural network identifies nonsteroidal anti-inflammatory drugs exacerbated respiratory disease (N-ERD) cohort
Tyrak, KE, Pajdzik, K, Konduracka, E, et al. Allergy. 2020; 75: 1649– 1658
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Data-driven step doses for drug provocation tests to nonsteroidal anti-inflammatory drugs
Nohra, D, Molinari, N, Demoly, P, Chiriac, A-M. Allergy. 2020; 75: 1423– 1434
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The role of drug, dose, and the tolerance/intolerance of new drugs in multiple drug hypersensitivity syndrome
Jörg, L, Yerly, D, Helbling, A, Pichler, W. Allergy. 2020; 75: 1178– 1187
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Secondary prevention measures in anaphylaxis patients: Data from the anaphylaxis registry
Kraft, M, Knop, MP, Renaudin, J-M, et al. Allergy. 2020; 75: 901– 910
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Interleukin 31 in insect bite hypersensitivity-Alleviating clinical symptoms by active vaccination against itch
Olomski, F, Fettelschoss, V, Jonsdottir, S, et al. Allergy. 2020; 75: 862– 871
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Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA-B*57:01 binding and T-cell activation
Thomson, PJ, Illing, PT, Farrell, J, et al. Allergy. 2020; 75: 636– 647
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Venom immunotherapy in patients with clonal mast cell disorders: IgG4 correlates with protection
Jarkvist, J, Salehi, C, Akin, C, Gülen, T. Allergy. 2020; 75: 169– 177
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Large local reactions to Hymenoptera stings: Outcome of re-stings in real life
ilò, MB, Martini, M, Pravettoni, V, et al. Allergy. 2019; 74: 1969– 1976
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Expression of the Tim3-galectin 9 axis is altered in drug-induced maculopapular exanthema
Fernandez-Santamaría, R, Palomares, F, Salas, M, et al. Allergy. 2019; 74: 1769– 1779
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Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01
Zhao, Q, Alhilali, K, Alzahrani, A, et al. Allergy. 2019; 74: 1533– 1548
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Increased expression of L-plastin in nasal polyp of patients with nonsteroidal anti-inflammatory drug-exacerbated respiratory disease
Takabayashi, T, Tanaka, Y, Susuki, D, et al. Allergy. 2019; 74: 1307- 1316
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Paired acute-baseline serum tryptase levels in perioperative anaphylaxis: An observational study
Vitte, J, Amadei, L, Gouitaa, M, et al. Allergy. 2019; 74: 1157– 1165
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The orphan nuclear receptor NR4A1 promotes FcεRI-stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis
Jin, F, Li, X, Deng, Y, et al. Allergy. 2019; 74: 1145– 1156
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Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria
Doña, I, Jurado-Escobar, R, Perkins, JR, et al. Allergy. 2019; 74: 1135– 1144
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Massive release of the histamine-degrading enzyme diamine oxidase during severe anaphylaxis in mastocytosis patients
Boehm, T, Reiter, B, Ristl, R, et al. Allergy. 2019; 74: 583– 593
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Active vaccination against interleukin-5 as long-term treatment for insect-bite hypersensitivity in horses
Fettelschoss-Gabriel, A, Fettelschoss, V, Olomski, F, et al. Allergy. 2019; 74: 572– 582
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Surfactant protein D alleviates eosinophil-mediated airway inflammation and remodeling in patients with aspirin-exacerbated respiratory disease
Choi, Y, Lee, D-H, Trinh, HKT, et al. Allergy. 2019; 74: 78– 88