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Indoor visible moulds and rhinitis in adults: the EGEA study

Orsi, L., Savouré, M., Bousquet, J., et al. Allergy. First published: 22 September 2022

Diagnostic value of a medical algorithm for investigation of perioperative hypersensitivity reactions

Sverrild, A., Carruthers, J., Murthee, K.G., et al. Allergy. First published: 22 September 2022

Nucleoside-modified mRNA vaccines yield robust blocking antibody responses against major house dust mite allergens

Jitthamstaporn, S., Inthong, R., Audomsun, D., et al. Allergy. First published: 22 September 2022

Legends of allergy and immunology: Lorenzo Moretta – unfolding the mysteries of NK cells and much more

Canonica, G.W. and Fauci, A.S. Allergy. First published: 20 September 2022

Legends of allergology and immunology: Alex Straumann

Simon, H.-U. Allergy. First published: 20 September 2022

Effect of indoor air pollution on atopic dermatitis in dogs

Lee, J.-H., Kang, B.-T. and Kim, H.-J. Allergy. First published: 20 September 2022

Disproportionate rate of female referrals for suspected COVID-19 vaccine allergies

Chiang, V., Kan, A.K.C., Yim, J.S.H., et al. Allergy. First published: 20 September 2022

Skin biomarkers predict development of atopic dermatitis in infancy

Rinnov, M.R., Halling, A.-S., Gerner, T., et al. Allergy. First published: 16 September 2022

The maternal prenatal and offspring early-life gut microbiome of childhood asthma phenotypes

Lee-Sarwar, K.A., Chen, Y.-C., Chen, Y.Y., et al. Allergy. First published: 15 September 2022

The changes of eosinophil counts in patients after treatment of dupilumab: A systematic review and meta-analysis

Zhou, B., Liang, S., Shang, S., Xiang, L. and Li, L.. Allergy. First published: 15 September 2022

circS100A11 enhances M2a macrophage activation and lung inflammation in children with asthma

Liang, Q., Fu, J., Wang, X., et al. Allergy. First published: 14 September 2022

Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T cell responses in humans

Lozano-Ojalvo, D., Tyler, S.R., Aranda, C.J., et al. Allergy. First published: 12 September 2022

Efficacy of FP-025, a novel Matrix metalloproteinase-12 (MMP-12) inhibitor in murine allergic asthma

Ravanetti, L., Dekker, T., Guo, L., et al. Allergy. First published: 12 September 2022

Real-world evidence for the long-term effect of allergen immunotherapy: current status on database-derived European studies

Vogelberg, C., Klimek, L., Brüggenjürgen, B. and Jutel, M. Allergy. First published: 08 September 2022

Obesity in women with asthma: baseline disadvantage plus greater small-airway responsiveness

Bourdin, A., Bommart, S., Marin, G., et al. Allergy. First published: 07 September 2022

Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis

Avlas, S, Shani, G, Rhone, N, et al. Allergy. First published: 07 September 2022

Allergic disease trajectories up to adolescence: Characteristics, early-life and genetic determinants

Kilanowski, A., Thiering, E., Wang, G., et al. Allergy. First published: 07 September 2022

Season of birth affects the risk of adult-onset asthma in Finland

Koskinen, A., Lemmetyinen, R., Luukkainen, A., et al. Allergy. First published: 06 September 2022

Mechanisms regulating neutrophil responses in immunity, allergy, and autoimmunity

Özcan, A. and Boyman, O. Allergy. First published: 06 September 2022

Updates in biologic therapy for chronic rhinosinusitis with nasal polyps and NSAID-exacerbated respiratory disease

Xu, X., Reitsma, S., Wang, D.Y. and Fokkens, W.J. Allergy. First published: 06 September 2022

Resensitisation in suspected penicillin allergy

Doña, I., Guidolin, L., Bogas, G., et al. Allergy. First published: 06 September 2022

In vitro vaccine challenge of PBMCs from BNT162b2 anaphylaxis patients reveal HSP90α-NOD2-NLRP3 nexus

Ko, H.L., Zhuo, N., Chang, Z.W., et al. Allergy. First published: 03 September 2022

Sputum transcriptome analysis of co-regulated genes related to arachidonic acid metabolism in N-ERD

Mastalerz, L., Kacorzyk, R., Jakieła, B., et al. Allergy. First published: 01 September 2022

Citations: 1581

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Citations: 474

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

Citations: 272

COVID-19 in a designated infectious diseases hospital outside Hubei Province, China

Cai, Q., Huang, D., Ou, P., Yu, H., Zhu, Z., Xia, Z. et al. Allergy. 2020; 75: 1742– 1752

Citations: 255

Risk factors for severe and critically ill COVID-19 patients: A review

Gao, Y-D, Ding, M, Dong, X, et al. Allergy. 2021; 76: 428– 455

Citations: 242

Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors

Radzikowska, U., Ding, M., Tan, G., Zhakparov, D., Peng, Y., Wawrzyniak, P. et al. Allergy. 2020; 75: 2828– 2844

Citations: 175

Eleven faces of coronavirus disease 2019

Dong, X., Cao, Y.-Y., Lu, X.-X., Zhang, Du, H., J.-J., Yan, Y.-Q. et al. Allergy. 2020; 75: 1699– 1709

Citations: 117

Type 2 immunity in the skin and lungs

Akdis, CA, Arkwright, PD, Brüggen, MC, et al. Allergy. 2020; 75: 1582– 1605

Citations: 97

The need for clean air: The way air pollution and climate change affect allergic rhinitis and asthma

Eguiluz-Gracia, I, Mathioudakis, AG, Bartel, S, et al. Allergy. 2020; 75: 2170– 2184

Citations: 92

Towards a more precise diagnosis of hypersensitivity to beta-lactams — an EAACI position paper

Romano, A, Atanaskovic-Markovic, M, Barbaud, A, et al. Allergy. 2020; 75: 1300– 1315

Citations: 89

Distinct characteristics of COVID-19 patients with initial rRT-PCR-positive and rRT-PCR-negative results for SARS-CoV-2

Zhang, J.-j., Cao, Y.-y., Dong, X., Wang, B.-c., Liao, M.-y., Lin, J. et al. Allergy. 2020; 75: 1809-1812

Citations: 88

Clinical characteristics of 182 pediatric COVID-19 patients with different severities and allergic status

Du, H, Dong, X, Zhang, J-J, et al. Allergy. 2021; 76: 510– 532

Citations: 83

Is asthma protective against COVID-19?

Carli, G., Cecchi, L., Stebbing, J., Parronchi, P. and Farsi, A. Allergy.2021; 76: 866-868

Citations: 81

Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement

Bousquet, J., Akdis, C.,A., Jutel, M., Bachert, C., Klimek, L., Agache, I. et al. Allergy. 2020; 75: 2440-2444

Citations: 81

Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic?

Gursel, M. and Gursel, I. Allergy. 2020; 75: 1815-1819

The EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Zuberbier, T., Aberer, W., Asero, R., Abdul Latiff, A., H., Baker, D., Ballmer-Weber, B. et al. Allergy. 2018; 73: 1393- 1414

Risk factors for severe and critically ill COVID-19 patients: A review

Gao, Y-D, Ding, M, Dong, X, et al. Allergy. 2021; 76: 428– 455

Vaccines and allergic reactions: the past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., Jain, S., Diamant, Z., Jesenak, M. et al. Allergy. 2021; 76: 1640-1660

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

EAACI guidelines: Anaphylaxis (2021 update)

Muraro, A, Worm, M, Alviani, C, et al. Allergy. 2022; 77: 357– 377

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A. et al. Allergy. 2008; 63: 8-160

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Advances and recent developments in asthma in 2020

Cevhertas, L, Ogulur, I, Maurer, DJ, et al. Allergy. 2020; 75: 3124– 3146

The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update

Maurer, M., Magerl, M., Betschel, S., et al. Allergy. First published: 10 January 2022

A compendium answering 150 questions on COVID-19 and SARS-CoV-2

Riggioni, C., Comberiati, P., Giovannini, M., Agache, I., Akdis, M., Alves-Correia, M. et al. Allergy. 2020; 75: 2503– 2541

Drug hypersensitivity, in vitro tools, biomarkers, and burden with COVID-19 vaccines

Palomares, F., Paris, J.L., Labella, M., Doña, I., Mayorga, C. and Torres, M.J. Allergy. First published: 01 August 2022

Exposure to avian coronavirus vaccines is associated with increased levels of SARS-CoV-2-cross-reactive antibodies

Ardicli, O, Carli, KT, Satitsuksanoa, P, et al. et al. Allergy. First published: 23 July 2022

Urticaria and/or angioedema secondary to mRNA COVID-19 vaccines: Updates from a United States case registry

Anvari, S., Samarakoon, U., Fu, X., et al. Allergy. First published: 16 July 2022

The nasopharyngeal and salivary microbiomes in COVID-19 patients with and without asthma

Kim, J.G., Zhang, A., Rauseo, A.M., et al. Allergy. First published: 15 July 2022

Management of suspected and confirmed COVID-19 (SARS-CoV-2) vaccine hypersensitivity

Worm, M., Alexiou, A., Bauer, A., et al. Allergy. First published: 20 June 2022

Immune-inflammatory proteome of elite ice hockey players before and after SARS-CoV-2 infection

Maurer, D.J., Barletta, E., Heider, A., et al. Allergy. First published: 12 June 2022

T cell recovery and evidence of persistent immune activation 12 months after severe COVID-19

Taeschler, P., Adamo, S., Deng, Y., et al. Allergy. First published: 14 May 2022

Long-term effects of homologous and heterologous SARS-CoV-2 vaccination on humoral and cellular immune responses

Hollstein, M.M., Münsterkötter, L., Schön, M.P., et al. Allergy. First published: 14 May 2022

COVID-19 in the absence of eosinophils: The outcome of confirmed SARS-CoV-2 infection whilst on treatment with benralizumab

Francis, C.H.R., Hearn, A.P., Ratnakumar, S., et al. Allergy. First published: 01 May 2022

Intranasal administration of a VLP-based vaccine induces neutralizing antibodies against SARS-CoV-2 and variants of concern

Rothen, D.A., Krenger, P.S., Nonic, A., et al. Allergy. First published: 11 April 2022

Autoantibodies in COVID-19 correlate with anti-viral humoral responses and distinct immune signatures

Taeschler, P., Cervia, C., Zurbuchen, Y., et al. Allergy. First published: 01 April 2022

Vaccine based on folded RBD-PreS fusion protein with potential to induce sterilizing immunity to SARS-CoV-2 variants

Gattinger, P., Kratzer, B., Tulaeva, I., et al. Allergy. First published: 31 March 2022

Are health care policies for COVID-19 evidence-based?

Bonini, S. and Fiorito, S. Allergy. First published: 30 March 2022

Virus-related stimuli modulate SARS-CoV-2 entry factor expression in pediatric tonsillar epithelial cells in vitro

Hara, M., Morimoto, N., Watabe, T., et al. Allergy. First published: 29 March 2022

Do basophil activation tests help elucidate allergic reactions to the ingredients in COVID-19 vaccines?

Eberlein, B., Sonja, M., Fischer, J., Darsow, U., Biedermann, T. and Brockow, K. Allergy. First published: 10 March 2022

Humoral immune response of Sinopharm/BBIBP COVID-19 vaccination before and after the booster immunization

Cheng, Z.J., Huang, H., Zheng, P., et al. Allergy. First published: 07 March 2022

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet, J., Agache, I., Blain, H., et al. Allergy. 2021; 76: 2952-2964

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review

Mostmans, Y., De Smedt, K., Richert, B., et al. Allergy. 2021; 76: 2998-3016

Eczema herpeticum in atopic dermatitis

Traidl, S., Roesner, L., Zeitvogel, J. and Werfel, T. Allergy. 2021; 76: 3017-3027

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp, T, Acar Şahin, A, Aggelidis, X, et al. Allergy. 2021; 76: 3041– 3052

Direct assessment of individual skin barrier components by electrical impedance spectroscopy

Mannweiler, R., Bergmann, S., Vidal-y-Sy, S., Brandner, J.M. and Günzel, D. Allergy. 2021; 76: 3094-3106

Prenatal paraben exposure and atopic dermatitis-related outcomes among children

Thürmann, L, Herberth, G, Seiwert, B, et al. Allergy. 2021; 76: 3122– 3132

Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis

Kopfnagel, V, Dreyer, S, Zeitvogel, J, et al. Allergy. 2021; 76: 3145– 3154

Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy

Tesfaye, A., Rodríguez-Nogales, A., Benedé, S., et al. Allergy. 2021; 76: 3183-3193

Sweet syndrome induced by SARS-CoV-2 Pfizer-BioNTech mRNA vaccine

Darrigade, A.-S., Théophile, H., Sanchez-Pena, P., et al. Allergy. 2021; 76: 3194-3196

Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma

Lommatzsch, M., Klein, M., Stoll, P. and Virchow, J.C. Allergy. 2021; 76: 3199-3202

Identification of Ulocladium chartarum as an important indoor allergen source

Pfeiffer, S., Sandler, P., Raith, M., et al. Allergy. 2021; 76: 3202-3206

Effects of allergen immunotherapy in the MASK-air study: a proof-of-concept analysis

Pfaar, O., Sousa-Pinto, B., Devillier, P., et al. Allergy. 2021; 76: 3212-3214

Legends of allergy and immunology: Sergio Bonini

Maltese, G. and Rasi, G. Allergy. 2021; 76: 3227-3229

Medical algorithm: Peri-operative management of mastocytosis patients

Bocca-Tjeertes, I.F.A., van de Ven, A.A.J.M., Koppelman, G.H., et al. Allergy. 2021; 76: 3233-3235

Junior Members Corner



Dear Junior Members,



The World Immune Regulation Meeting (WIRM) was held in Davos, Switzerland, from 6 to 9 July 2022 after two consecutive years with an online format

The meeting focused on “Immune Activation, Effector Functions and Immune Tolerance with a special focus on Autoimmunity and Allergy”. We had the opportunity to learn first-hand from more than 40 top-speakers from around the world. The topics, divided in twelve, ranged from T and B cell activation to immunity against viral infections -including COVID-19-, novel vaccine development and inflammation in cancer. In addition, we were able to enjoy 12 workshops with more than 60 speakers and 11 poster sessions with more than 70 presenters.

The congress was a total success! As in previous editions, the meeting allowed the participants to directly interact with top scientists in the field, not only during the meeting sessions and workshops, but also during the networking events and inspiring poster sessions while enjoying a delicious dinner. Not to mention the idyllic scenery of Davos and the warm welcome of the Swiss Institute of Allergy and Asthma Research (SIAF) members and the organising committee.

We encourage you to participate in the next WIRM, an ideal congress for both basic and clinical researchers, which will be held in 5-8 July 2023.

Keep you up to date with the latest news by clicking here




WIRM 2022



WIRM 2022

Best regards,
The Junior Member Assembly