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MAIT Cells Suppress IgE-Mediated Asthma via IFNγ-Dependent B Cell Regulation

A.M.Cannata, J.W.McAlees, J.M.Hargis, et al.Allergy. First published:07 May 2026

Cost-Effectiveness of Allergen Immunotherapy for Allergic Rhinitis: A Systematic Review

J.Jacob, A.Fong, C.Joyce, et al.Allergy. First published:06 May 2026

Silica Aggravates Steroid Hyporesponsiveness via STING Activation in House Dust Mite Lung Inflammation

B.Mdkhana, N.S.Sharif-Askari, M.W.Eladham, et al.Allergy. First published:06 May 2026

Ultra-Processed Food Consumption and Childhood Allergic Diseases: Increased Risk of Asthma Onset in the SENDO Project

O.Galindo, M.J.Goikoetxea, L.Moreno-Galarraga, et al.Allergy. First published:05 May 2026

Algorithms in Allergy: Elevated IgE in Pediatric Patients

B.Kolukisa, A.P.S.Arinc, C.Ozdemir, et al.Allergy. First published:04 May 2026

Trace Elements in Allergy: Narrative Review

M.Ordak, M.Zemelka-Wiacek, A.Kosowska, et al.Allergy. First published:04 May 2026

Pollen-Pharmacotherapy Interaction Impacts Symptom Control in Seasonal Allergic Rhinitis

Z.Zhang, M.Wang, X.Wang, et al.Allergy. First published:04 May 2026

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

N.J.Campion, S.Villazala-Merino, C.Morgenstern, et al.Allergy. First published:04 May 2026

Algorithms of Patient Selection for Allergen Immunotherapy

U.P.Zieglmayer, S.Arasi, T.Eiwegger, et al.Allergy. First published:02 May 2026

Determinants of Immunoglobulin-G N-Glycan Patterns in the Aging General Population

S.Leonard, R.Heijmans, V.A.S.H.Dalm, et al.Allergy. First published:30 April 2026

TNF Pathway-Mediated Tolerogenic T-Cell Trajectory Driven by Allergen Immunotherapy

H.S.Charles, A.A.Gabr, S.Wang, et al.Allergy. First published:30 April 2026

Longitudinal Follow-Up of Gut and Salivary Microbiota in Children With Food Protein-Induced Enterocolitis Syndrome

A.Lemoine, K.Adel-Patient, N.Kapel, et al.Allergy. First published:28 April 2026

Resolving Endoplasmic Reticulum-Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

P.S.Pathinayake, A.C.Brown, N.T.Awatade, et al.Allergy. First published:26 April 2026

Optimising the Diagnosis of Sesame Seed Allergy With the Basophil Activation Test

R.Foong, I.Bartha, H.Boyd, et al.Allergy. First published:26 April 2026

Nematode in Cockroaches: A Potential Allergen Source

D.Kang, M.Yi, J.H.Choi, et al.Allergy. First published:24 April 2026

Obituary: Sergio Del Giacco (1936–2026)

S.Bonini, M.J.Torres, M.Shamji, et al.Allergy. First published:23 April 2026

Mast Cells in Acute COVID-19 Patients

I.Zaffran, H.Pahima, E.Ben-Chetrit, et al.Allergy. First published:22 April 2026

Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of ARIA Experts

M.C.Urbano, R.J.Vieira, Y.Xiang, et al.Allergy. First published:18 April 2026

Adrenaline, Anaphylaxis, and Experimental Evidence

J.D.Godsell, J.A.Trubiano.Allergy. First published:18 April 2026

Identification of Shared Regulators of IgE- and MRGPRX2-Dependent Degranulation in Human Mast Cells

J.Folkerts, P.Tienen, M.J.W.Bruijn, et al.Allergy. First published:18 April 2026

Intestinal STING-(Over)activation—A Contributing Factor to Food Allergies?

S.Goebel, H.R.Schiller.Allergy. First published:18 April 2026

Differential Effects of Benralizumab and Mepolizumab on Pro-Resolving Mediators

J.Bernaola, J. A.Cañas, Á.Arranz-Fragua, et al.Allergy. First published:17 April 2026

Obituary: Professor Dietrich Kraft (1937-2026)

H.Breiteneder, B.Bohle, K.Hoffmann-Sommergruber, et al.Allergy. First published:16 April 2026

Urticaria and Angioedema: When East Meets West—and the Middle

J.Peter, A.Jindal, S.D.Giacco, et al.Allergy. First published:15 April 2026

IgE And IgG Antibody Responses to α-Gal and Association With Carotid Stenosis in Swedish Patients

M.Perusko, D.Apostolovic, J.Grundström, et al.Allergy. First published:12 April 2026

Citations: 342

The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

Zuberbier, T, Abdul Latiff, AH, Abuzakouk, M, Aquilina, S, Asero, R, Baker, D, et al. Allergy. 2022; 77: 734– 766

Citations: 147

EAACI guidelines: Anaphylaxis (2021 update)

Muraro A, Worm M, Alviani C, et al. Allergy. 2022; 77: 357–377

Citations: 118

The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update

Maurer M, Magerl M, Betschel S, et al. Allergy. 2022; 77: 1961–1990

Citations: 118

The role of peripheral blood eosinophil counts in COVID-19 patients

Xie, G, Ding, F, Han, L, Yin, D, Lu, H, Zhang, M. Allergy. 2021; 76: 471– 482

Citations: 114

Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Celebi Sozener Z, Ozdel Ozturk B, Cerci P, et al. Allergy. 2022; 77: 1418–1449

Citations: 105

Basophil activation test: Mechanisms and considerations for use in clinical trials and clinical practice

Santos, A.F., Alpan, O. and Hoffmann, H.-J. Allergy. 2021; 76: 2420-2432

Citations: 90

EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID-19 vaccines

Sokolowska, M., Eiwegger, T., Ollert, M., Torres, M.J., Barber, D., Del Giacco, S., et al. Allergy. 2021; 76: 1629-1639

Citations: 88/h5>

The role of allergen-specific IgE, IgG and IgA in allergic disease

Shamji MH, Valenta R, Jardetzky T, et al. Allergy. 2021; 76: 3627–3641

Citations: 82

COVID-19 pandemic: Practical considerations on the organization of an allergy clinic—An EAACI/ARIA Position Paper

Pfaar, O, Klimek, L, Jutel, M, Akdis, C, A, Bousquet, J, Breiteneder, H, et al. Allergy. 2021; 76: 648– 676

Citations: 81

Advances and highlights in allergic rhinitis

Zhang Y, Lan F, Zhang L. Allergy. 2021; 76: 3383–3389

Citations: 79

Allergic reactions to the first COVID-19 vaccine: A potential role of polyethylene glycol?

Cabanillas, B., Akdis, C.A. and Novak, N. Allergy. 2021; 76: 1617-1618

Citations: 76

Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: A systematic review for the EAACI guidelines

Agache, I., Song, Y., Alonso-Coello, P., Vogel, Y., Rocha, C., Solà, I., et al. Allergy. 2021; 76: 2337-2353

Citations: 74

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Citations: 73

Endotypes of chronic rhinosinusitis: Relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches

Kato A, Peters AT, Stevens WW, Schleimer RP, Tan BK, Kern RC. Allergy. 2022; 77: 812–826

Citations: 70

Vaccines and allergic reactions: The past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., et al. Allergy. 2021; 76: 1640-1660

Citations: 69

Advances and highlights in biomarkers of allergic diseases

Ogulur I, Pat Y, Ardicli O, et al. Allergy. 2021; 76: 3659–3686

Citations: 69

Regulatory B cells, A to Z

Jansen, K., Cevhertas, L., Ma, S., Satitsuksanoa, P., Akdis, M. and van de Veen, W.

Citations: 62

Advances and highlights in asthma in 2021

Agache I, Eguiluz-Gracia I, Cojanu C, et al. Allergy. 2021; 76: 3390–3407

Citations: 62

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Citations: 61

The ingenious mast cell: Contemporary insights into mast cell behavior and function

Dahlin, J.S., Maurer, M., Metcalfe, D.D., Pejler, G., Sagi-Eisenberg, R. and Nilsson, G. Allergy. 2022; 2022; 77: 83-99

The EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Zuberbier, T., Aberer, W., Asero, R., Abdul Latiff, A., H., Baker, D., Ballmer-Weber, B. et al. Allergy. 2018; 73: 1393- 1414

Risk factors for severe and critically ill COVID-19 patients: A review

Gao, Y-D, Ding, M, Dong, X, et al. Allergy. 2021; 76: 428– 455

Vaccines and allergic reactions: the past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., Jain, S., Diamant, Z., Jesenak, M. et al. Allergy. 2021; 76: 1640-1660

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

EAACI guidelines: Anaphylaxis (2021 update)

Muraro, A, Worm, M, Alviani, C, et al. Allergy. 2022; 77: 357– 377

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A. et al. Allergy. 2008; 63: 8-160

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Advances and recent developments in asthma in 2020

Cevhertas, L, Ogulur, I, Maurer, DJ, et al. Allergy. 2020; 75: 3124– 3146

The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update

Maurer, M., Magerl, M., Betschel, S., et al. Allergy. First published: 10 January 2022

A compendium answering 150 questions on COVID-19 and SARS-CoV-2

Riggioni, C., Comberiati, P., Giovannini, M., Agache, I., Akdis, M., Alves-Correia, M. et al. Allergy. 2020; 75: 2503– 2541

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet, J., Agache, I., Blain, H., et al. Allergy. 2021; 76: 2952-2964

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review

Mostmans, Y., De Smedt, K., Richert, B., et al. Allergy. 2021; 76: 2998-3016

Eczema herpeticum in atopic dermatitis

Traidl, S., Roesner, L., Zeitvogel, J. and Werfel, T. Allergy. 2021; 76: 3017-3027

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp, T, Acar Şahin, A, Aggelidis, X, et al. Allergy. 2021; 76: 3041– 3052

Direct assessment of individual skin barrier components by electrical impedance spectroscopy

Mannweiler, R., Bergmann, S., Vidal-y-Sy, S., Brandner, J.M. and Günzel, D. Allergy. 2021; 76: 3094-3106

Prenatal paraben exposure and atopic dermatitis-related outcomes among children

Thürmann, L, Herberth, G, Seiwert, B, et al. Allergy. 2021; 76: 3122– 3132

Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis

Kopfnagel, V, Dreyer, S, Zeitvogel, J, et al. Allergy. 2021; 76: 3145– 3154

Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy

Tesfaye, A., Rodríguez-Nogales, A., Benedé, S., et al. Allergy. 2021; 76: 3183-3193

Sweet syndrome induced by SARS-CoV-2 Pfizer-BioNTech mRNA vaccine

Darrigade, A.-S., Théophile, H., Sanchez-Pena, P., et al. Allergy. 2021; 76: 3194-3196

Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma

Lommatzsch, M., Klein, M., Stoll, P. and Virchow, J.C. Allergy. 2021; 76: 3199-3202

Identification of Ulocladium chartarum as an important indoor allergen source

Pfeiffer, S., Sandler, P., Raith, M., et al. Allergy. 2021; 76: 3202-3206

Effects of allergen immunotherapy in the MASK-air study: a proof-of-concept analysis

Pfaar, O., Sousa-Pinto, B., Devillier, P., et al. Allergy. 2021; 76: 3212-3214

Legends of allergy and immunology: Sergio Bonini

Maltese, G. and Rasi, G. Allergy. 2021; 76: 3227-3229

Medical algorithm: Peri-operative management of mastocytosis patients

Bocca-Tjeertes, I.F.A., van de Ven, A.A.J.M., Koppelman, G.H., et al. Allergy. 2021; 76: 3233-3235

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Junior Members Corner




Dear Junior Members,



Our Junior Member representatives actively participated in the American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting, held in Philadelphia (February 27–March 2). Under the motto “Advancing Precision Medicine from Discovery to Patient Care,” our EAACI JMA representatives had the opportunity to exchange experiences and engage in discussions with AAAAI Fellows-in-Training. This interaction opened the door to new collaborations between our academies, supporting the professional development of our junior members and reinforcing the strong commitment to cooperation between both institutions. In addition, they contributed to increasing EAACI’s visibility at the congress booth and participated in several EAACI organized sessions, including “European Perspective on Immunomodulation in Food Allergy.”

More recently, JMA representatives also provided strong support at the EAACI Spring Meeting, held in Belgrade, Serbia (March 27–29), under the motto “Prevention as Treatment: A New Paradigm.” Alongside an excellent scientific program and presentations from our junior members, the meeting placed a strong emphasis on networking and engagement with national societies from the Balkan region. The goal was to strengthen collaborations, identify unmet needs, and explore synergies to improve the diagnosis, management, and care of patients with allergic diseases.

The collaboration among junior members was a clear example of the value of teamwork and represents an important step forward in strengthening partnerships between national societies within EAACI. This is already driving the development of new educational and scientific initiatives.


EAACI Winter School


EAACI Winter School

Best regards,
The Junior Member Assembly


EAACI Patients Organisation Committee Corner



HIGHLIGHTS FROM PAAM 2025



A group of ten Patient Organisations Committee (POC) members gathered at this wonderful venue in Palau de Congressos de Palma, Mallorca for 2025 Pediatric Allergy and Asthma Focused Meeting. Many had speaker slots giving lived experience perspectives of having children living with allergy and risk of anaphylaxis. So the EAACI PAAM Congress theme of ‘Inspiring insights for every family’ really resonated with us.

As POC, we are with EAACI to help where we can and it brings the science to a person experience, centred level. We had members a wide range of participants from Chile, USA, Turkey, UK, Sweden, Switzerland, France, Italy, Greece and Spain as POC has 36 POC members in 24 countries.

Our Chair, Ozlem Ceylan, gave an overview at the Opening Ceremony on why EAACI awareness campaigns matter, from awareness to action, so patients can feel heard and patient organisations can help lobby for policy change in their country.

POC participated in the Student Awareness Day that was set to educate 40 students aged 14-16 about allergic diseases and emergency response, with the local organising committee’s support.

One of our POC members, Esther Esteban Arroyo opened “The sister society session” with SEICAP and introduced their patient organisation, AEPNAA and their activities in Spain.

Mikaela Odemyr from Swedish Asthma and Allergy Association joined the Anaphylaxis session with a heartfelt talk, “When My Child Had Anaphylaxis: Expectations vs. Reality”. Fallon Schultz from IFPIES USA, gave a wonderful talk on parents’ perspective of dealing with a child’s FPIES journey and introduced their resources to support caregivers. On the last day of PAAM, Maria Zioga from Greece, gave a great talk, “From panic to preparedness: Building trust and resilience in food allergy care” and highlighted the importance of safety for food allergic children.