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Prevalence of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease Patients With Frequent Exacerbations

M. C.Melles, J. C. C. M.Veen, D.-J.Slebos, et al.Allergy. First published: 24 March 2026

Malassezia-Induced Type 2 Immunity in Head Neck Shoulder Type Atopic Dermatitis

I.Suhrkamp, T.Heidland, C.Saft,et al.Allergy. First published: 24 March 2026

Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward

E. H.Kim, J. A.Bird, H. A.Brough, et al.Allergy. First published: 23 March 2026

The Impact of Early Childhood Caries on Asthma Trajectories During the First 15 Years of Life

Handoko, C., Singh, A., Dharmage, S.C., et al.Allergy. First published: 23 March 2026

Frequency and Severity of Allergic Reactions to Non-Mandatory Labelled Allergenic Foods—Data From Two Large European Cohorts

S.Dölle-Bierke, A.Gonzalo-Fernández, D.Sabouraud-Leclerc, et al.Allergy. First published: 23 March 2026

Increased Primary Cilia Contribute to Airway Epithelium Remodeling in Asthma

G.Chen, H.Jie, C.Huang, et al.Allergy. First published: 23 March 2026

Chinese Position Paper on Biologic Therapy for Allergic Rhinitis

Y.Zhang, J.Li, X.Li, et al.Allergy. First published: 23 March 2026

The Minimal Clinically Important Difference in Allergen Immunotherapy: The Rocky Road Toward an Evidence-Based Value

Hartenstein, D., Schmidt, S., Mahler, V. and Kaul, S.Allergy. First published:20 March 2026

Fel d 1-Expressing Plant-Derived Bioparticle: A Novel Treatment for Cat Allergy

J. A.Layhadi, L. C.Gutierrez, S. T.Keane,et al.Allergy. First published: 19 March 2026

Involvement of B Cell Subsets in Patients With Steven Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)

F.Ahmad, J. M. P.Mateo, F. E.Joy, et al.Allergy. First published: 17 March 2026

Sphingosine 1-Phosphate Receptor 1 and 5 Reciprocally Regulate IL-13 and IL-9 Production in Atopic Dermatitis

K.Yamamura, S.Garcet, J.Gonzalez, et al.Allergy. First published: 17 March 2026

Family Size and Food Allergy in Early Childhood: The Japan Environment and Children's Study

T.Nomura, H.Tanida, T.Inoue,et al.Allergy. First published: 15 March 2026

Switching Long-Term Prophylaxis to Donidalorsen for Hereditary Angioedema: 1-Year OASISplus Results

M. A.Riedl, J. A.Bernstein, J. S.Jacobs,et al.Allergy. First published: 14 March 2026

Legends of Allergology/Immunology: Marcus Maurer (†)—Physician, Scientist, Allergist and Unbeatable Communicator

L.Klimek, M.Metz, P.Staubach, and T.Zuberbier. Allergy. First published: 13 March 2026

Non-Invasive Scalp Tape-Strip RNA Sequencing Captures Disease Activity and Treatment-Response Signatures in Alopecia Areata

Mochón-Jiménez, C., Gay-Mimbrera, J., Dávila-Flores, V., et al.Allergy. First published: 13 March 2026

A Case for Anti-IgE Vaccination

P.Engeroff, Z.Gharailoo, M.Vogel, and M. F.Bachmann. Allergy. First published: 11 March 2026

Nasal Airway Transcriptome Reflects Selected Asthma-Associated Gene Signatures in the Lower Airways

H.Wen, T.Kole, O. A.Carpaij, et al.Allergy. First published: 10 March 2026

Childhood Fractional Exhaled Nitric Oxide Predicts Incident Allergic Rhinitis in Adolescence and Young Adulthood

C.-H.Wang, J.-L.Huang, H.-J.Tsai, et al.Allergy. First published: 09 March 2026

The OX40/OX40L Axis Promotes Th2 Activity and Impairs Regulatory T Cell Function in Atopic Dermatitis

K.Yamamura, D.Dahabreh, E.Del Duca, et al.Allergy. First published: 07 March 2026

Chitin Is a Potent Inducer of Type 2 Airway Inflammation Independent of Endogenous Chitinolytic Activity

J.Declercq, H.Aegerter, U.Smole, et al.Allergy. First published: 06 March 2026

Algorithms in Allergy: Diagnosis and Treatment of Pollen Food Syndrome

R.Asero, L.Cecchi, V.Pravettoni, E.Scala, and D.Villalta. Allergy. First published: 06 March 2026

Making Peanuts Safer: Autoclaving as a Heat and Pressure Strategy to Increase Peanut Tolerability

Stodulski, D., Garcia-Medina, G. and Cabanillas, B. Allergy. First published: 06 March 2026

Effect of Intramuscular Adrenaline on Histamine-Induced Hypotension: A Randomised Placebo-Controlled Pilot Trial

M.Weiss-Tessbach, A. M.Dizdarevic, T.Bischof, et al.Allergy. First published: 02 March 2026

Algorithms in Allergy: General Allergen Molecule-Based Algorithm for Allergen-Specific Immunotherapy

H.-J.Huang, D.Trifonova, P.Gattinger, et al.Allergy. First published: 02 March 2026

The Evolution of Sesame Seed Allergy Over Time

R.-X.Foong, G.Du Toit, H. T.Bahnson, et al. Allergy. First published: 02 March 2026

Legends of Allergy—Lawrence B. Schwartz

G. P.Nilsson. Allergy. First published: 02 March 2026

Citations: 342

The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

Zuberbier, T, Abdul Latiff, AH, Abuzakouk, M, Aquilina, S, Asero, R, Baker, D, et al. Allergy. 2022; 77: 734– 766

Citations: 147

EAACI guidelines: Anaphylaxis (2021 update)

Muraro A, Worm M, Alviani C, et al. Allergy. 2022; 77: 357–377

Citations: 118

The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update

Maurer M, Magerl M, Betschel S, et al. Allergy. 2022; 77: 1961–1990

Citations: 118

The role of peripheral blood eosinophil counts in COVID-19 patients

Xie, G, Ding, F, Han, L, Yin, D, Lu, H, Zhang, M. Allergy. 2021; 76: 471– 482

Citations: 114

Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Celebi Sozener Z, Ozdel Ozturk B, Cerci P, et al. Allergy. 2022; 77: 1418–1449

Citations: 105

Basophil activation test: Mechanisms and considerations for use in clinical trials and clinical practice

Santos, A.F., Alpan, O. and Hoffmann, H.-J. Allergy. 2021; 76: 2420-2432

Citations: 90

EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID-19 vaccines

Sokolowska, M., Eiwegger, T., Ollert, M., Torres, M.J., Barber, D., Del Giacco, S., et al. Allergy. 2021; 76: 1629-1639

Citations: 88/h5>

The role of allergen-specific IgE, IgG and IgA in allergic disease

Shamji MH, Valenta R, Jardetzky T, et al. Allergy. 2021; 76: 3627–3641

Citations: 82

COVID-19 pandemic: Practical considerations on the organization of an allergy clinic—An EAACI/ARIA Position Paper

Pfaar, O, Klimek, L, Jutel, M, Akdis, C, A, Bousquet, J, Breiteneder, H, et al. Allergy. 2021; 76: 648– 676

Citations: 81

Advances and highlights in allergic rhinitis

Zhang Y, Lan F, Zhang L. Allergy. 2021; 76: 3383–3389

Citations: 79

Allergic reactions to the first COVID-19 vaccine: A potential role of polyethylene glycol?

Cabanillas, B., Akdis, C.A. and Novak, N. Allergy. 2021; 76: 1617-1618

Citations: 76

Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: A systematic review for the EAACI guidelines

Agache, I., Song, Y., Alonso-Coello, P., Vogel, Y., Rocha, C., Solà, I., et al. Allergy. 2021; 76: 2337-2353

Citations: 74

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Citations: 73

Endotypes of chronic rhinosinusitis: Relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches

Kato A, Peters AT, Stevens WW, Schleimer RP, Tan BK, Kern RC. Allergy. 2022; 77: 812–826

Citations: 70

Vaccines and allergic reactions: The past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., et al. Allergy. 2021; 76: 1640-1660

Citations: 69

Advances and highlights in biomarkers of allergic diseases

Ogulur I, Pat Y, Ardicli O, et al. Allergy. 2021; 76: 3659–3686

Citations: 69

Regulatory B cells, A to Z

Jansen, K., Cevhertas, L., Ma, S., Satitsuksanoa, P., Akdis, M. and van de Veen, W.

Citations: 62

Advances and highlights in asthma in 2021

Agache I, Eguiluz-Gracia I, Cojanu C, et al. Allergy. 2021; 76: 3390–3407

Citations: 62

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Citations: 61

The ingenious mast cell: Contemporary insights into mast cell behavior and function

Dahlin, J.S., Maurer, M., Metcalfe, D.D., Pejler, G., Sagi-Eisenberg, R. and Nilsson, G. Allergy. 2022; 2022; 77: 83-99

The EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Zuberbier, T., Aberer, W., Asero, R., Abdul Latiff, A., H., Baker, D., Ballmer-Weber, B. et al. Allergy. 2018; 73: 1393- 1414

Risk factors for severe and critically ill COVID-19 patients: A review

Gao, Y-D, Ding, M, Dong, X, et al. Allergy. 2021; 76: 428– 455

Vaccines and allergic reactions: the past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., Jain, S., Diamant, Z., Jesenak, M. et al. Allergy. 2021; 76: 1640-1660

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

EAACI guidelines: Anaphylaxis (2021 update)

Muraro, A, Worm, M, Alviani, C, et al. Allergy. 2022; 77: 357– 377

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A. et al. Allergy. 2008; 63: 8-160

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Advances and recent developments in asthma in 2020

Cevhertas, L, Ogulur, I, Maurer, DJ, et al. Allergy. 2020; 75: 3124– 3146

The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update

Maurer, M., Magerl, M., Betschel, S., et al. Allergy. First published: 10 January 2022

A compendium answering 150 questions on COVID-19 and SARS-CoV-2

Riggioni, C., Comberiati, P., Giovannini, M., Agache, I., Akdis, M., Alves-Correia, M. et al. Allergy. 2020; 75: 2503– 2541

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet, J., Agache, I., Blain, H., et al. Allergy. 2021; 76: 2952-2964

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review

Mostmans, Y., De Smedt, K., Richert, B., et al. Allergy. 2021; 76: 2998-3016

Eczema herpeticum in atopic dermatitis

Traidl, S., Roesner, L., Zeitvogel, J. and Werfel, T. Allergy. 2021; 76: 3017-3027

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp, T, Acar Şahin, A, Aggelidis, X, et al. Allergy. 2021; 76: 3041– 3052

Direct assessment of individual skin barrier components by electrical impedance spectroscopy

Mannweiler, R., Bergmann, S., Vidal-y-Sy, S., Brandner, J.M. and Günzel, D. Allergy. 2021; 76: 3094-3106

Prenatal paraben exposure and atopic dermatitis-related outcomes among children

Thürmann, L, Herberth, G, Seiwert, B, et al. Allergy. 2021; 76: 3122– 3132

Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis

Kopfnagel, V, Dreyer, S, Zeitvogel, J, et al. Allergy. 2021; 76: 3145– 3154

Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy

Tesfaye, A., Rodríguez-Nogales, A., Benedé, S., et al. Allergy. 2021; 76: 3183-3193

Sweet syndrome induced by SARS-CoV-2 Pfizer-BioNTech mRNA vaccine

Darrigade, A.-S., Théophile, H., Sanchez-Pena, P., et al. Allergy. 2021; 76: 3194-3196

Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma

Lommatzsch, M., Klein, M., Stoll, P. and Virchow, J.C. Allergy. 2021; 76: 3199-3202

Identification of Ulocladium chartarum as an important indoor allergen source

Pfeiffer, S., Sandler, P., Raith, M., et al. Allergy. 2021; 76: 3202-3206

Effects of allergen immunotherapy in the MASK-air study: a proof-of-concept analysis

Pfaar, O., Sousa-Pinto, B., Devillier, P., et al. Allergy. 2021; 76: 3212-3214

Legends of allergy and immunology: Sergio Bonini

Maltese, G. and Rasi, G. Allergy. 2021; 76: 3227-3229

Medical algorithm: Peri-operative management of mastocytosis patients

Bocca-Tjeertes, I.F.A., van de Ven, A.A.J.M., Koppelman, G.H., et al. Allergy. 2021; 76: 3233-3235

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Junior Members Corner




Dear Junior Members,



The EAACI Immunology Winter School 2026 was held in Sierra Nevada, Spain, bringing together 70 juniors selected based on their submitted scientific abstracts. The meeting was designed as an interactive and discussion-driven forum, placing young researchers at the centre of scientific exchange alongside internationally recognised faculty.

The programme combined keynote lectures with abstract presentations by juniors, ensuring direct engagement between young scientists and experts. In addition, poster sessions generated lively discussions and constructive feedback. Moreover, a dedicated Practical Course provided hands-on exposure to advanced technologies and analytical approaches, offering methodological insights readily applicable to ongoing research.

To further promote interaction among participants, and in addition to the traditional networking activities, a dedicated networking hour was organised for the first time this edition. During this session, groups of juniors had the opportunity to share experiences and ask questions to experts in a relaxed atmosphere. Topics beyond science were also discussed, including the unmet needs in biomedical sciences, opportunities for juniors, and key recommendations on how to progress in their scientific careers. Interesting debates emerged around the issues that most concern and interest junior researchers, with experts sharing their perspectives on the future of the field.

The Winter School fostered strong international networking and direct expert accessibility, enabling detailed discussions on research projects and career development. Participants benefited from focused feedback, new collaborations, and an immersive scientific atmosphere that reinforced EAACI’s commitment to supporting early-career investigators.


EAACI Winter School


EAACI Winter School

Best regards,
The Junior Member Assembly


EAACI Patients Organisation Committee Corner



HIGHLIGHTS FROM PAAM 2025



A group of ten Patient Organisations Committee (POC) members gathered at this wonderful venue in Palau de Congressos de Palma, Mallorca for 2025 Pediatric Allergy and Asthma Focused Meeting. Many had speaker slots giving lived experience perspectives of having children living with allergy and risk of anaphylaxis. So the EAACI PAAM Congress theme of ‘Inspiring insights for every family’ really resonated with us.

As POC, we are with EAACI to help where we can and it brings the science to a person experience, centred level. We had members a wide range of participants from Chile, USA, Turkey, UK, Sweden, Switzerland, France, Italy, Greece and Spain as POC has 36 POC members in 24 countries.

Our Chair, Ozlem Ceylan, gave an overview at the Opening Ceremony on why EAACI awareness campaigns matter, from awareness to action, so patients can feel heard and patient organisations can help lobby for policy change in their country.

POC participated in the Student Awareness Day that was set to educate 40 students aged 14-16 about allergic diseases and emergency response, with the local organising committee’s support.

One of our POC members, Esther Esteban Arroyo opened “The sister society session” with SEICAP and introduced their patient organisation, AEPNAA and their activities in Spain.

Mikaela Odemyr from Swedish Asthma and Allergy Association joined the Anaphylaxis session with a heartfelt talk, “When My Child Had Anaphylaxis: Expectations vs. Reality”. Fallon Schultz from IFPIES USA, gave a wonderful talk on parents’ perspective of dealing with a child’s FPIES journey and introduced their resources to support caregivers. On the last day of PAAM, Maria Zioga from Greece, gave a great talk, “From panic to preparedness: Building trust and resilience in food allergy care” and highlighted the importance of safety for food allergic children.