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An Algorithm for the Diagnosis and Treatment of Allergic Contact Dermatitis (ACD)

J.D.Johansen, W.Uter, I.R.White, et al.Allergy. First published:13 August 2026

Hazelnut and Walnut Vicilins in Tree Nut Allergy: Co-Sensitization Patterns and Clinical Severity Associations

D.Villalta, G.Marcassa, G.Cusa, et al.Allergy. First published:12 August 2026

Influence of Environmental Pollution on Basophil Reactivity to Birch Pollen Allergens in Atopic and Non-Atopic Subjects

M.Czarnobilska, M.Bulanda, E.Czarnobilska, et al.Allergy. First published:11 August 2026

Expanding the Utility of Gold Nanocluster “Allergolds” to Peanut Allergen Ara h 2

G.O.Leighton, V.Martinez-Macias, E.R.D.Diavoukana, et al.Allergy. First published:10 August 2026

Mycosis Fungoides-Like Atopic Dermatitis Represents a Th22-Dominant Inflammatory Endotype

J.H.Lee, S.H.Lim, H.Kook, et al.Allergy. First published:06 August 2026

Plasma Metabolomes Identify Distinct Asthma Metabotypes: Findings From the COREA Cohort

W.Chae, J.An, C.E.Lee, et al.Allergy. First published:05 August 2026

Serum-Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity-Linked Signatures

J.S.Lally, T.Yoshida, S.Gao, et al.Allergy. First published:31 July 2026

Dupilumab in Cholinergic Urticaria: An Exploratory Phase 2 Investigator-Initiated Study

A.Gutsche, W.Grabowska, S.Altrichter, et al.Allergy. First published:31 July 2026

Efficacy of Full and Limited Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal Polyps: A Randomised Controlled Trial

P.Virkkula, S.Hammarén-Malmi, A.Laulajainen-Hongisto, et al.Allergy. First published:30 July 2026

Dietary Habits and Atopic Dermatitis Significantly Influence the Fecal Microbiome

D.Fehr, N.Flack, G.Masenga, et al.Allergy. First published:28 July 2026

Allergen Protease Act d 1 Induces TLR4-Dependent Inflammation via Ectodomain Cleavage

M. Zlatanova, I. Hafner-Bratkovič, and M. Gavrović-Jankulović.Allergy. First published:28 July 2026

Allergenicity of α-Gal-Containing Products

F.B.Mangaard, E.Eller, P.S.Skov, et al.Allergy. First published:28 July 2026

Distinct Immunometabolic Profiles in Finnish and Russian Karelian Adolescents With Contrasting Allergy Risk

N.Fyhrquist, M.Riskumäki, P.Karisola, et al.Allergy. First published:24 July 2026

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

E.F.Ventura, J.Corriger, H.Omer, et al.Allergy. First published:24 July 2026

Urinary Leukotriene E4 Enables Rule-In Diagnosis of NSAID-Exacerbated Respiratory Disease

M.Orihara, A.Maus, P.M.Vanderboom, et al.Allergy. First published:23 July 2026

The Airway Transcriptome in Type 2 Cytokine Biomarker-High and -Low Severe Asthma

J.Shen, R.Chaudhuri, S.Bicknell, et al.Allergy. First published:20 July 2026

Association of IgE Sialylation With IgE-Mediated Allergy Diseases

J. Álvarez, N.Parody, C.Cacheiro-Llaguno, et al.Allergy. First published:20 July 2026

Shotgun Metagenomics Reveals Skin Microbiome Composition and Function in Infant Atopic Disease

Z.Shen, J.K.Eckert, R.Saffery, et al.Allergy. First published:17 July 2026

Time-Resolved Multi-Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination

A.Olivera, B.Schwarz, B.Dulek, et al.Allergy. First published:17 July 2026

Citations: 342

The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

Zuberbier, T, Abdul Latiff, AH, Abuzakouk, M, Aquilina, S, Asero, R, Baker, D, et al. Allergy. 2022; 77: 734– 766

Citations: 147

EAACI guidelines: Anaphylaxis (2021 update)

Muraro A, Worm M, Alviani C, et al. Allergy. 2022; 77: 357–377

Citations: 118

The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update

Maurer M, Magerl M, Betschel S, et al. Allergy. 2022; 77: 1961–1990

Citations: 118

The role of peripheral blood eosinophil counts in COVID-19 patients

Xie, G, Ding, F, Han, L, Yin, D, Lu, H, Zhang, M. Allergy. 2021; 76: 471– 482

Citations: 114

Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Celebi Sozener Z, Ozdel Ozturk B, Cerci P, et al. Allergy. 2022; 77: 1418–1449

Citations: 105

Basophil activation test: Mechanisms and considerations for use in clinical trials and clinical practice

Santos, A.F., Alpan, O. and Hoffmann, H.-J. Allergy. 2021; 76: 2420-2432

Citations: 90

EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID-19 vaccines

Sokolowska, M., Eiwegger, T., Ollert, M., Torres, M.J., Barber, D., Del Giacco, S., et al. Allergy. 2021; 76: 1629-1639

Citations: 88/h5>

The role of allergen-specific IgE, IgG and IgA in allergic disease

Shamji MH, Valenta R, Jardetzky T, et al. Allergy. 2021; 76: 3627–3641

Citations: 82

COVID-19 pandemic: Practical considerations on the organization of an allergy clinic—An EAACI/ARIA Position Paper

Pfaar, O, Klimek, L, Jutel, M, Akdis, C, A, Bousquet, J, Breiteneder, H, et al. Allergy. 2021; 76: 648– 676

Citations: 81

Advances and highlights in allergic rhinitis

Zhang Y, Lan F, Zhang L. Allergy. 2021; 76: 3383–3389

Citations: 79

Allergic reactions to the first COVID-19 vaccine: A potential role of polyethylene glycol?

Cabanillas, B., Akdis, C.A. and Novak, N. Allergy. 2021; 76: 1617-1618

Citations: 76

Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: A systematic review for the EAACI guidelines

Agache, I., Song, Y., Alonso-Coello, P., Vogel, Y., Rocha, C., Solà, I., et al. Allergy. 2021; 76: 2337-2353

Citations: 74

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Citations: 73

Endotypes of chronic rhinosinusitis: Relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches

Kato A, Peters AT, Stevens WW, Schleimer RP, Tan BK, Kern RC. Allergy. 2022; 77: 812–826

Citations: 70

Vaccines and allergic reactions: The past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., et al. Allergy. 2021; 76: 1640-1660

Citations: 69

Advances and highlights in biomarkers of allergic diseases

Ogulur I, Pat Y, Ardicli O, et al. Allergy. 2021; 76: 3659–3686

Citations: 69

Regulatory B cells, A to Z

Jansen, K., Cevhertas, L., Ma, S., Satitsuksanoa, P., Akdis, M. and van de Veen, W.

Citations: 62

Advances and highlights in asthma in 2021

Agache I, Eguiluz-Gracia I, Cojanu C, et al. Allergy. 2021; 76: 3390–3407

Citations: 62

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Citations: 61

The ingenious mast cell: Contemporary insights into mast cell behavior and function

Dahlin, J.S., Maurer, M., Metcalfe, D.D., Pejler, G., Sagi-Eisenberg, R. and Nilsson, G. Allergy. 2022; 2022; 77: 83-99

The EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Zuberbier, T., Aberer, W., Asero, R., Abdul Latiff, A., H., Baker, D., Ballmer-Weber, B. et al. Allergy. 2018; 73: 1393- 1414

Risk factors for severe and critically ill COVID-19 patients: A review

Gao, Y-D, Ding, M, Dong, X, et al. Allergy. 2021; 76: 428– 455

Vaccines and allergic reactions: the past, the current COVID-19 pandemic, and future perspectives

Sampath, V., Rabinowitz, G., Shah, M., Jain, S., Diamant, Z., Jesenak, M. et al. Allergy. 2021; 76: 1640-1660

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

EAACI guidelines: Anaphylaxis (2021 update)

Muraro, A, Worm, M, Alviani, C, et al. Allergy. 2022; 77: 357– 377

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A. et al. Allergy. 2008; 63: 8-160

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Advances and recent developments in asthma in 2020

Cevhertas, L, Ogulur, I, Maurer, DJ, et al. Allergy. 2020; 75: 3124– 3146

The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update

Maurer, M., Magerl, M., Betschel, S., et al. Allergy. First published: 10 January 2022

A compendium answering 150 questions on COVID-19 and SARS-CoV-2

Riggioni, C., Comberiati, P., Giovannini, M., Agache, I., Akdis, M., Alves-Correia, M. et al. Allergy. 2020; 75: 2503– 2541

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet, J., Agache, I., Blain, H., et al. Allergy. 2021; 76: 2952-2964

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review

Mostmans, Y., De Smedt, K., Richert, B., et al. Allergy. 2021; 76: 2998-3016

Eczema herpeticum in atopic dermatitis

Traidl, S., Roesner, L., Zeitvogel, J. and Werfel, T. Allergy. 2021; 76: 3017-3027

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp, T, Acar Şahin, A, Aggelidis, X, et al. Allergy. 2021; 76: 3041– 3052

Direct assessment of individual skin barrier components by electrical impedance spectroscopy

Mannweiler, R., Bergmann, S., Vidal-y-Sy, S., Brandner, J.M. and Günzel, D. Allergy. 2021; 76: 3094-3106

Prenatal paraben exposure and atopic dermatitis-related outcomes among children

Thürmann, L, Herberth, G, Seiwert, B, et al. Allergy. 2021; 76: 3122– 3132

Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis

Kopfnagel, V, Dreyer, S, Zeitvogel, J, et al. Allergy. 2021; 76: 3145– 3154

Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy

Tesfaye, A., Rodríguez-Nogales, A., Benedé, S., et al. Allergy. 2021; 76: 3183-3193

Sweet syndrome induced by SARS-CoV-2 Pfizer-BioNTech mRNA vaccine

Darrigade, A.-S., Théophile, H., Sanchez-Pena, P., et al. Allergy. 2021; 76: 3194-3196

Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma

Lommatzsch, M., Klein, M., Stoll, P. and Virchow, J.C. Allergy. 2021; 76: 3199-3202

Identification of Ulocladium chartarum as an important indoor allergen source

Pfeiffer, S., Sandler, P., Raith, M., et al. Allergy. 2021; 76: 3202-3206

Effects of allergen immunotherapy in the MASK-air study: a proof-of-concept analysis

Pfaar, O., Sousa-Pinto, B., Devillier, P., et al. Allergy. 2021; 76: 3212-3214

Legends of allergy and immunology: Sergio Bonini

Maltese, G. and Rasi, G. Allergy. 2021; 76: 3227-3229

Medical algorithm: Peri-operative management of mastocytosis patients

Bocca-Tjeertes, I.F.A., van de Ven, A.A.J.M., Koppelman, G.H., et al. Allergy. 2021; 76: 3233-3235

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Junior Members Corner



Dear Juniors,

EAACI Congress 2026 in Istanbul once again provided an outstanding opportunity for Junior Members to engage with the latest advances in allergy and clinical immunology while connecting with colleagues from across Europe and beyond. Bringing together clinicians, scientists and healthcare professionals from a wide range of disciplines, the congress fostered an inspiring environment for scientific exchange, collaboration and professional development.

For many Junior Members, the congress represented far more than attending lectures. It offered the opportunity to present research, discuss new ideas with internationally recognised experts, receive valuable feedback and build collaborations with peers from different institutions and countries. Dedicated sessions organised by the Junior Member Assembly (JMA) encouraged lively discussions on emerging topics across the specialty, providing an interactive platform for learning, exchanging experiences and showcasing the high-quality research being conducted by Junior Members.

Alongside the scientific programme, the JMA supported a range of educational and networking initiatives designed to promote the professional development of early-career members. Activities such as the EAACI Allergy College, the Clinical Research Challenge and the Junior Members Mentorship Programme created opportunities to strengthen mentoring relationships, develop new skills and establish international connections that often continue well beyond the congress itself. Together, these initiatives reflect EAACI’s continued commitment to supporting the next generation of allergy and clinical immunology professionals.

Perhaps the greatest strength of the EAACI Congress is the sense of community it creates. Whether attending for the first time or returning as experienced participants, Junior Members have the opportunity to become part of a collaborative international network united by a shared passion for research, education and improving patient care. We look forward to welcoming even more Junior Members to future EAACI meetings and encourage you to make the most of the many opportunities the JMA and the wider Academy provide throughout the year.

Best regards,
The Junior Member Assembly


EAACI Patients Organisation Committee Corner



HIGHLIGHTS FROM PAAM 2025



A group of ten Patient Organisations Committee (POC) members gathered at this wonderful venue in Palau de Congressos de Palma, Mallorca for 2025 Pediatric Allergy and Asthma Focused Meeting. Many had speaker slots giving lived experience perspectives of having children living with allergy and risk of anaphylaxis. So the EAACI PAAM Congress theme of ‘Inspiring insights for every family’ really resonated with us.

As POC, we are with EAACI to help where we can and it brings the science to a person experience, centred level. We had members a wide range of participants from Chile, USA, Turkey, UK, Sweden, Switzerland, France, Italy, Greece and Spain as POC has 36 POC members in 24 countries.

Our Chair, Ozlem Ceylan, gave an overview at the Opening Ceremony on why EAACI awareness campaigns matter, from awareness to action, so patients can feel heard and patient organisations can help lobby for policy change in their country.

POC participated in the Student Awareness Day that was set to educate 40 students aged 14-16 about allergic diseases and emergency response, with the local organising committee’s support.

One of our POC members, Esther Esteban Arroyo opened “The sister society session” with SEICAP and introduced their patient organisation, AEPNAA and their activities in Spain.

Mikaela Odemyr from Swedish Asthma and Allergy Association joined the Anaphylaxis session with a heartfelt talk, “When My Child Had Anaphylaxis: Expectations vs. Reality”. Fallon Schultz from IFPIES USA, gave a wonderful talk on parents’ perspective of dealing with a child’s FPIES journey and introduced their resources to support caregivers. On the last day of PAAM, Maria Zioga from Greece, gave a great talk, “From panic to preparedness: Building trust and resilience in food allergy care” and highlighted the importance of safety for food allergic children.