Biomarkers
Biomarkers are measurable indicators of biological processes,
disease states, or responses to treatment. In medicine, biomarkers
play a crucial role in diagnosis, prognosis, and treatment
monitoring. Recent advancements in biomarker research have led to
the discovery of novel markers for various diseases, including
cancer, cardiovascular disorders, and autoimmune conditions. In the
field of allergy and immunology, biomarkers are increasingly being
used to improve the diagnosis and management of allergic diseases.
These biomarkers provide valuable information about disease
activity, severity, and response to treatment.
Recent studies have focused on identifying biomarkers for conditions
such as asthma, allergic rhinitis, and food allergy, with the aim of
improving patient care and outcomes. The latest developments in
biomarker research have paved the way for personalized medicine
approaches, allowing for more targeted and effective treatments. By
better understanding the role of biomarkers in allergic diseases,
researchers hope to develop new diagnostic tests and therapeutic
strategies that will ultimately improve the lives of millions of
allergy sufferers worldwide.
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81 Articles |
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Biomarkers of peanut allergy in children over time
Foong R-X, Du Toit G, van Ree R, et al. Allergy. First published: 18 June 2024
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Immunoglobulin free light chains in severe asthma patient: Could they be a new biomarker?
Caruso C, Ciasca G, Baglivo I, et al. Allergy. First published: 29 February 2024
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Transcriptomic evaluation of skin tape-strips in children with allergic asthma uncovers epidermal barrier dysfunction and asthma-associated biomarkers abnormalities
Del Duca E, Dahabreh D, Kim M, et al. Allergy. First published: 20 February 2024
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AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI-EANO position paper
Turner MC, Radzikowska U, Ferastraoaru DE, et al. Allergy. First published: 24 January 2024
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Reply to corresponcence: “Oral immunotherapy in alpha-gal red meat allergy: Could specific IgE be a potential biomarker in monitoring management?”
Ünal, D., Eyice-Karabacak, D., Kutlu, A., et al. Allergy. First published: 19 April 2024
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Oral immunotherapy in alpha-gal red meat allergy: Could specific IgE be a potential biomarker in monitoring management?
Unal D, Eyice-Karabacak D, Kutlu A, et al. Allergy. First published: 07 August 2023
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Peripheral biomarkers for predicting sputum eosinophilia in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease
Trąd, G., Sanak, M., Ćmiel, A., et al. Allergy. First published: 12 June 2023
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Patient-centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA-EAACI approach - ARIA-EAACI Task Force Report
Bousquet J, Shamji MH, Anto JM, et al. Allergy. First published: 11 April 2023
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IAngiomotin and angiostatin as asthma biomarkers: Implications for the regulation of airway remodeling and inflammation
Lee PH, Choi S, An M, et al. Allergy. First published: 18 January 2023
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IL-13, periostin and dipeptidyl-peptidase-4 reveal endotype-phenotype associations in atopic dermatitis
Maintz, L., Welchowski, T., Herrmann, N., et al. Allergy. First published: 17 January 2023
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Extracellular vesicle microRNA signatures as novel biomarkers in obese asthmatics
Sundar IK, Prasad C, Duraisamy SK. Allergy. First published: 21 December 2023
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Effect of abrocitinib on skin biomarkers in patients with moderate-to-severe atopic dermatitis
Guttman-Yassky E, Facheris P, Gomez-Arias PJ, et al. Allergy. First published: 18 December 2023
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Biomarkers of immediate drug hypersensitivity
Mayorga C, Ariza A, Muñoz-Cano R, Sabato V, Doña I, Torres MJ. Allergy. First published: 10 November 2023
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Nutritional metabolites as biomarker for food intake to improve dietary-based randomized control trials
Venter, C. and Frei, R. Allergy. First published: 22 November 2022
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Biomarkers associated with the development of comorbidities in patients with atopic dermatitis: a systematic review
Broderick, C., Ziehfreund, S., van Bart, K., et al. Allergy. First published: 10 November 2022
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Development of sensitization to peanut and storage proteins and relation to markers of airway and systemic inflammation – a 24-year follow up
Tedner, S.G., Klevebro, S., Bergström, A., Kull, et al. Allergy. First published: 31 October 2022
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Biomarkers of asthma relapse and lung function decline in adults with spontaneous asthma remission: a population-based cohort study
Tan, D.J., Lodge, C.J., Walters, E.H., et al. Allergy. First published: 27 October 2022
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Furan fatty acid metabolite in newborns predicts risk of asthma
Gürdeniz, G., Kim, M., Brustad, N., et al. Allergy. First published: 27 October 2022
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Specific IgE against the house dust mite allergens Der p 5, 20 and 21 influences the phenotype and severity of atopic diseases
Walsemann, T., Böttger, M., Traidl, S., et al. Allergy. First published: 14 October 2022
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Biomarkers enable prediction of tacrolimus resistance in patients with severe allergic conjunctivitis
Okada N, Yazu H, Shimizu E, et al. Allergy. First published: 114 October 2022
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Delayed type hypersensitivity reactions to various allergens may differently model inflammatory skin diseases
Pavel, A.B., Del Duca, E., Cheng, J., et al. Allergy. First published: 30 September 2022
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Skin biomarkers predict development of atopic dermatitis in infancy
Rinnov MR, Halling AS, Gerner T, et al. Allergy. First published: 30 September 2022
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RNA sequencing of single allergen-specific memory B cells after grass pollen immunotherapy: two unique cell fates and CD29 as a biomarker for treatment effect
McKenzie, C.I., Varese, N., Aui, P.M., et al. Allergy. First published: 25 September 2022
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Skin biomarkers predict development of atopic dermatitis in infancy
Rinnov, M.R., Halling, A.-S., Gerner, T., et al. Allergy. First published: 16 September 2022
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Fungal exposome, human health and unmet needs: a 2022 update with special focus on allergy
Vitte, J., Michel, M., Malinovschi, A., et al. Allergy. First published: 17 August 2022
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Serum exosome inflamma-miRs are surrogate biomarkers for asthma phenotype and severity
Vázquez-Mera, S., Martelo-Vidal, L., Miguéns-Suárez, P., et al. Allergy. First published: 16 August 2022
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Urine eosinophil-derived neurotoxin: a potential marker of activity in select eosinophilic disorders
Makiya, M.A., Khoury, P., Kuang, F.L., et al. Allergy. First published: 02 August 2022
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Drug hypersensitivity, in vitro tools, biomarkers, and burden with COVID-19 vaccines
Palomares, F., Paris, J.L., Labella, M., Doña, I., Mayorga, C. and Torres, M.J. Allergy. First published: 01 August 2022
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Dupilumab reduced impact of severe exacerbations on lung function in patients with moderate-to-severe type 2 asthma
Papi, A., Corren, J., Castro, M., et al. Allergy. First published: 28 July 2022
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Patient-centered dupilumab dosing regimen leads to successful dose reduction in persistently controlled atopic dermatitis
Spekhorst, L.S., Bakker, D., Drylewicz, J., et al. Allergy. First published: 15 July 2022
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Relationship between inflammatory status and microbial composition in severe asthma and during exacerbation
Diver, S., Haldar, K., McDowell, P.J., et al. Allergy. First published: 01 July 2022
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Omics technologies in allergy and asthma research: an EAACI position paper
Radzikowska, U., Baerenfaller, K., Cornejo-Garcia, J.A., et al. Allergy. First published: 17 June 2022
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Airway remodelling rather than cellular infiltration characterises both type2 cytokine biomarker-high and -low severe asthma
Khalfaoui, L., Symon, F.A., Couillard, S., et al. Allergy. First published: 17 May 2022
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Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis
Turner, P.J., Arasi, S., Ballmer-Weber, B., et al. Allergy. First published: 20 April 2022
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Platelet-activating factor acetylhydrolase is a biomarker of severe anaphylaxis in children
Upton, J.E.M., Hoang, J.A., Leon-Ponte, M.,et al. Allergy. First published: 09 April 2022
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Preterm birth reduces the risk of IgE sensitization up to early adulthood: A population-based birth cohort study
Mitselou, N, Andersson, N, Bergström, A, et al. Allergy. First published: 06 September 2021
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Coordinated IgG2 and IgE responses as a marker of allergen immunotherapy efficacy
Bordas-Le Floch, V, Berjont, N, Batard, T, et al. Allergy. First published: 22 September 2021
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Identification of novel biomarkers to distinguish bradykinin-mediated angioedema from mast cell-/histamine-mediated angioedema
Bindke, G., Gehring, M., Wieczorek, D., Kapp, A., Buhl, T. and Wedi, B. Allergy. First published: 20 July 2021
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Methylation risk scores for childhood aeroallergen sensitization: Results from the LISA birth cohort
Kilanowski, A., Chen, J., Everson, T., et al. Allergy. First published: 19 April 2022
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Electrical impedance spectroscopy for the characterization of skin barrier in atopic dermatitis
Rinaldi, A.O., Korsfeldt, A., Ward, S. et al. Allergy. First published: 08 April 2021
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Baseline type 2 biomarker levels and response to tezepelumab in severe asthma
Corren, J., Pham, T.-H., Gil, E.G., et al. Allergy. First published: 16 December 2021
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Platelet-activating factor acetylhydrolase: A biomarker in hymenoptera venom allergy?
Bilò, M.B., Corsi, A., Martini, M., et al. Allergy. First published: 29 October 2021
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Assessment of biomarkers in pediatric atopic dermatitis by tape strips and skin biopsies
Andersson, A.M., Sølberg, J., Koch, A., et al. Allergy. First published: 25 October 2021
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DAAB-V2: Updated database of allergy and asthma biomarkers
Majumdar, S., Bhattacharjee, S., Jana, T. and Saha, S. Allergy. First published: 20 September 2021
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Sputum antinuclear antibody serves as a biomarker for severe asthma
Luu, Q.Q., Cao, T.B.T., Shin, Y.-S., Yang, E.-M., Moon, J.-Y. and Park, H.-S. Allergy. First published: 16 September 2021
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Advances and highlights in biomarkers of allergic diseases
Ogulur, I., Pat, Y., Ardicli, O., et al. Allergy. First published: 14 September 2021
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Unique molecular signatures typify skin inflammation induced by chemical allergens and irritants
Lefevre, M.-A., Nosbaum, A., Rozieres, A., et al. Allergy. First published: 26 June 2021
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Medical Algorithms: Approach to adult asthma exacerbations
Nair, P. and O’Byrne, P.M. Allergy. First published: 04 June 2021
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The role of allergen-specific IgE, IgG and IgA in allergic disease
Shamji, M.H., Valenta, R., Jardetzky, T. et al. Allergy. First published: 17 May 2021
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Noninvasive biomarkers identify eosinophilic esophagitis: A prospective longitudinal study in children
Wechsler, J.B., Ackerman, S.J., Chehade, M., et al. Allergy. First published: 27 April 2021
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Biologics and airway remodeling in severe asthma
Varricchi G., Ferri S., Pepys J., et al. Allergy. 2022;77(12):3538-3552
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Highlights in the advances of chronic rhinosinusitis
Xu, X., Reitsma, S., Wang, D.Y. and Fokkens, W.J. Allergy. 2021; 76: 3349-3358
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A new era of atopic eczema research: Advances and highlights
Hülpüsch, C, Weins, AB, Traidl-Hoffmann, C, Reiger, M. Allergy. 2021; 76: 3408-3421
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Advances and highlights in asthma in 2021
Agache, I, Eguiluz-Gracia, I, Cojanu, C, et al. Allergy. 2021; 76: 3390-3407
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Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma
Lommatzsch, M., Klein, M., Stoll, P. and Virchow, J.C. Allergy. 2021; 76: 3199-3202
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High-dimensional analysis defines multicytokine T-cell subsets and supports a role for IL-21 in atopic dermatitis
Czarnowicki, T., Kim, H.J., Villani, et al. Allergy. 2021; 76: 3080-3093
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An integrated scalp and blood biomarker approach suggeststhe systemic nature of alopecia areata
Glickman, J.W., Dubin, C., Dahabreh, D., et al. Allergy. 2021; 76: 3053-3065
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Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review
Mostmans, Y., De Smedt, K., Richert, B., Elieh Ali Komi, D., Maurer, M. and Michel, O. et al. Allergy. 2021; 76: 2998-3016
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Predictors of treatment response in chronic spontaneous urticaria
Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981
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Increased day-to-day fluctuations in exhaled breath profiles after a rhinovirus challenge in asthma
Lammers, A., Brinkman, P., te Nijenhuis, L.H., et al. Allergy.2021; 76: 2488-2499
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Glycomics in tears: seeking for new biomarkers for ocular allergy diagnosis
Fauquert, J.-L. and Kowalski, M.L. Allergy.2021; 76: 2335-2336
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Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST
Maspero, J.F., FitzGerald, J.M., Pavord, I.D., et al.Allergy.2021; 76: 2621-2624
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Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment
Niessen, N.M., Gibson, P.G., Baines, K.J., et al. Allergy. 2021; 76: 2090-2101
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Interleukin-6: A novel biomarker for monoclonal antibody and chemotherapy-associated hypersensitivity confirms a cytokine release syndrome phenotype-endotype association
Jakubovic, B.D., Sanchez-Sanchez, S., Hamadi, S., Lynch, D.-M. and Castells, M.Allergy.2021; 76: 1571-1573
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Basophil activation and serum IL-5 levels as possible monitor biomarkers in severe eosinophilic asthma patients treated with anti-IL-5 drugs
Caruso, C., Colantuono, S., Tolusso, B., et al.Allergy.2021; 76: 1569-1571
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Identification of Pru du 6 as a potential marker allergen for almond allergy
Kabasser, S, Hafner, C, Chinthrajah, S, et al. Allergy. 2021; 76: 1463– 1472
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Predicting persistence of atopic dermatitis in children using clinical attributes and serum proteins
Lauffer, F, Baghin, V, Standl, M, et al. Allergy. 2021; 76: 1158– 1172
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Basophil activation test : A diagnostic, predictive and monitoring assay for allergen immunotherapy
Alpan, O., Layhadi, J.A., Ulrik Sønder, S., Li, H. and Shamji, M.H. Allergy.2021; 76: 1321-1324
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Exploring novel systemic biomarker approaches in grass-pollen sublingual immunotherapy using omics
Barker-Tejeda, TC, Bazire, R, Obeso, D, et al. Allergy. 2021; 76: 1199– 1212
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Blood myeloperoxidase-DNA, a biomarker of early response to SARS-CoV-2 infection?
Guéant, J.-L., Fromonot, J., Guéant-Rodriguez, R.-M., Lacolley, P., Guieu, R. and Regnault, V.Allergy.2021; 76: 892-896
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Circulating microRNA-15b-5p as a biomarker for asthma-COPD overlap
Hirai, K, Shirai, T, Shimoshikiryo, T, et al. Allergy. 2021; 76: 766– 774
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Plasma adenosine is linked to disease activity and response to treatment in patients with chronic spontaneous urticaria
Mao, M, Liu, H, Yan, S, et al.Allergy. 2021; 76: 571– 573
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Clinical, radiological, and laboratory characteristics and risk factors for severity and mortality of 289 hospitalized COVID-19 patients
Zhang, J-J, Cao, Y-Y, Tan, G, et al. Allergy. 2021; 76: 533– 550
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The role of peripheral blood eosinophil counts in COVID-19 patients
Xie, G, Ding, F, Han, L, Yin, D, Lu, H, Zhang, M. Allergy. 2021; 76: 471– 482
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Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics
Zounemat Kermani, N., Saqi, M., Agapow, P., et al. Allergy.2021; 76: 380-383
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RNA-seq–based profiling of extracellular vesicles in plasma reveals a potential role of miR-122-5p in asthma
Bahmer, T., Krauss-Etschmann, S., Buschmann, D., et al. Allergy. 2021; 76: 366-371
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Tape strips from early-onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin
Pavel A. B., Renert- Yuval, Y., Wu, J., et al. Allergy. 2021; 76: 314- 325
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Th2 cell markers in peripheral blood increase during an acute asthma exacerbation
Palikhane N. S. et al. Allergy. 2021; 76:281-290
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Phenotyping peach-allergic patients sensitized to lipid transfer protein and analysing severity biomarkers
Bogas, G, Muñoz-Cano, R, Mayorga, C, et al. Allergy. 2020; 75: 3228– 3236
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Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria: Results of the PURIST Study
Schoepke, N, Asero, R, Ellrich, A, et al. Allergy. 2019; 74: 2427– 2436