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When platelets meet candidalysin: “we just Wnt to have fun”

Bulut, O., Geckin, B. and Domínguez-Andrés, J. Allergy. First published: 24 January 2022

Climate change and global health: A call to more research and more action

Agache, I., Sampath, V., Aguilera, J., et al. Allergy. First published: 24 January 2022

World Health Organization Global Air Quality Guideline recommendations: Executive summary

Goshua, A., Akdis, C. and Nadeau, K.C. Allergy. First published: 21 January 2022

Ten year trends of national healthcare costs of asthma, allergic rhinitis and atopic eczema in 3 million Norwegians

Parr, C.L., Nystad, W., Karlstad, Ø., et al. Allergy. First published: 20 January 2022

Differential effects of lung inflammation on insulin resistance in humans and mice

Karlina, R., Flexeder, C., Musiol, S., et al. Allergy. First published: 20 January 2022

Development of the EAACI% season definition a backup for a global application

Bastl, M., Berger, M., Bastl, K., et al. Allergy. First published: 19 January 2022

TFEB signaling attenuates NLRP3-driven inflammatory responses in severe asthma

Theofani, E., Semitekolou, M., Samitas, K., et al. Allergy. First published: 17 January 2022

The prevalence of non-allergic rhinitis phenotypes in the general population: a cross-sectional study

Avdeeva, K.S., Fokkens, W.J., Segboer, C.L. and Reitsma, S. Allergy. First published: 17 January 2022

Dupilumab improves health-related quality of life in severe chronic rhinosinusitis with nasal polyps

Lee, S.E., Hopkins, C., Mullol, J., et al. Allergy. First published: 16 January 2022

Word of mouth: oral mucosa composition in health and immune disease

Delgado-Dolset, M., Rodriguez-Coira, J. and Sanchez-Solares, J. Allergy. First published: 14 January 2022

Higher Levels of Bacterial DNA in Serum Associate with Severe and Fatal COVID-19

Lunjani, N., Albrich, W.C., Suh, N., et al. Allergy. First published: 12 January 2022

A phase 2, randomized multi oral immunotherapy with omalizumab ‘real life’ study

Sindher, S.B., Kumar, D., Cao, S., et al. Allergy. First published: 11 January 2022

The international WAO/EAACI guideline for the management of hereditary angioedema – the 2021 revision and update

Maurer, M., Magerl, M., Betschel, S., et al. Allergy. First published: 10 January 2022

Allergen immunotherapy and/or biologicals for IgE-mediated food allergy: systematic review and meta-analysis

de Silva, D., Rodríguez del Río, P., de Jong, N.W., et al. Allergy. First published: 09 January 2022

Cashew oral immunotherapy for desensitizing cashew-pistachio allergy (Nut CRACKER study)

Elizur, A., Appel, M.Y., Nachshon, L., et al. Allergy. First published: 09 January 2022

Prodromes as predictors of hereditary angioedema attacks

Leibovich-Nassi, I., Reshef, A., Somech, R. and Golander, H. Allergy. First published: 09 January 2022

Serum periostin among infants with severe bronchiolitis and risk of developing asthma: A prospective multicenter cohort study

Nanishi, M., Fujiogi, M., Freishtat, R.J., et al. Allergy. First published: 09 January 2022

Bet v 1 and other birch allergens are more resistant to proteolysis and more abundant than other birch pollen proteins

Cabrera, A., Foo, A.C., Fitzgerald, M.C. and Mueller, G.A. Allergy. First published: 07 January 2022

Thrombin cleaves IL-33 and modulates IL-33-activated allergic lung inflammation

Huang, Y., Li, X., Zhu, L., Huang, C., et al. Allergy. First published: 07 January 2022

The past, present and future of allergic diseases in China

Zhang, L. and Akdis, C.A. Allergy. First published: 07 January 2022

Serological testing for SARS-CoV-2 antibodies in clinical practice: a comparative diagnostic accuracy study

Horn, M.P., Jonsdottir, H.R., Brigger, D., et al. Allergy. First published: 05 January 2022

Comparing biologicals for severe chronic rhinosinusitis with nasal polyps: a network meta-analysis

Boechat, J.L., Silva, D., Sousa-Pinto, B. and Delgado, L. Allergy. First published: 03 January 2022

EAACI position paper on the clinical use of the bronchial allergen challenge: unmet needs and research priorities

Agache, I., Antolin-Amerigo, D., de Blay, F., et al. Allergy. First published: 02 January 2022

“Too high, too low”: the complexities of using thresholds in isolation to inform precautionary allergen (“may contain”) labels

Turner, P.J., Baumert, J.L., Beyer, K., et al. Allergy. First published: 29 December 2021

Gender specific decline in perioperative allergic reactions in Norway after withdrawal of pholcodine

Malvik, L.B., De Pater, G.H., Dahle, G.O. and Guttormsen, A.B. Allergy. First published: 28 December 2021

Development and validation of combined symptom-medication scores for allergic rhinitis

Sousa-Pinto, B., Filipe Azevedo, L., Jutel, M., et al. Allergy. First published: 21 December 2021

Citations: 1524

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Citations: 374

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

Citations: 245

COVID-19 in a designated infectious diseases hospital outside Hubei Province, China

Cai, Q., Huang, D., Ou, P., Yu, H., Zhu, Z., Xia, Z. et al. Allergy. 2020; 75: 1742– 1752

Citations: 190

Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors

Radzikowska, U., Ding, M., Tan, G., Zhakparov, D., Peng, Y., Wawrzyniak, P. et al. Allergy. 2020; 75: 2828– 2844

Citations: 149

Eleven faces of coronavirus disease 2019

Dong, X., Cao, Y.-Y., Lu, X.-X., Zhang, Du, H., J.-J., Yan, Y.-Q. et al. Allergy. 2020; 75: 1699– 1709

Citations: 98

Risk factors for severe and critically ill COVID-19 patients: A review

Gao, Y-D, Ding, M, Dong, X, et al. Allergy. 2021; 76: 428– 455

Citations: 85

Distinct characteristics of COVID-19 patients with initial rRT-PCR-positive and rRT-PCR-negative results for SARS-CoV-2

Zhang, J.-j., Cao, Y.-y., Dong, X., Wang, B.-c., Liao, M.-y., Lin, J. et al. Allergy. 2020; 75: 1809-1812

Citations: 76

Type 2 immunity in the skin and lungs

Akdis, CA, Arkwright, PD, Brüggen, MC, et al. Allergy. 2020; 75: 1582– 1605

Citations: 71

Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement

Bousquet, J., Akdis, C.,A., Jutel, M., Bachert, C., Klimek, L., Agache, I. et al. Allergy. 2020; 75: 2440-2444

Citations: 69

Towards a more precise diagnosis of hypersensitivity to beta-lactams — an EAACI position paper

Romano, A, Atanaskovic-Markovic, M, Barbaud, A, et al. Allergy. 2020; 75: 1300– 1315

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Azkur, A.,K., Akdis, M., Azkur, D., Sokolowska, M., van de Veen, W., Brüggen, M.,C. et al. Allergy. 2020; 75: 1564– 1581

Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China

Zhang, J.-J., Dong, X., Cao, Y.-Y., Yuan, Y.-D., Yan, Y.-Q., Akdis, C., A. and Gao, Y.-D. Allergy. 2020; 75: 1730– 1741

Unexplained recurrent fever: when is autoinflammation the explanation?

Kallinich, T., Gattorno, M., Grattan, C.,E., de Koning, H.,D., Traidl-Hoffmann, C., Feist, E., et al. Allergy. 2013; 68: 285– 296

The EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Zuberbier, T., Aberer, W., Asero, R., Abdul Latiff, A., H., Baker, D., Ballmer-Weber, B. et al. Allergy. 2018; 73: 1393- 1414

A compendium answering 150 questions on COVID-19 and SARS-CoV-2

Riggioni, C., Comberiati, P., Giovannini, M., Agache, I., Akdis, M., Alves-Correia, M. et al. Allergy. 2020; 75: 2503– 2541

Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Bousquet, J., Anto, J.M., Czarlewski, W., Haahtela, T. Fonseca, S.,C., Iaccarino, G. et al. Allergy. 2021; 76: 735– 750

Eleven faces of coronavirus disease 2019

Dong, X., Cao, Y.-Y., Lu, X.-X., Zhang, Du, H., J.-J., Yan, Y.-Q. et al. Allergy. 2020; 75: 1699– 1709

Thirty-six COVID-19 cases preventively vaccinated with mumps-measles-rubella vaccine: All mild course

Larenas-Linnemann, D.,E. and Rodríguez-Monroy, F. Allergy. 2021; 76: 910-914

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A. et al. Allergy. 2008; 63: 8-160

Asthma and COVID-19: Is asthma a risk factor for severe outcomes?

Johnston, S.,L. Allergy. 2020; 75: 1543-1545

Serological testing for SARS-CoV-2 antibodies in clinical practice: A comparative diagnostic accuracy study

Horn, MP, Jonsdottir, HR, Brigger, D, et al. Allergy. First published: 05 January 2022

Mast cell activation is associated with post-acute COVID-19 syndrome

Wechsler, J.B., Butuci, M., Wong, A., Kamboj, A.P. and Youngblood, B.A. Allergy. First published: 25 November 2021

Analysis of BNT162b2- and CVnCoV-elicited sera and of convalescent sera toward SARS-CoV-2 viruses

Hein, S, Herrlein, M-L, Mhedhbi, I, et al. Allergy. First published: 25 November 2021

Experience with polyethylene glycol allergy-guided risk management for COVID-19 vaccine anaphylaxis

Brockow, K., Mathes, S., Fischer, J., et al. Allergy. First published: 22 November 2021

COVID-19 vaccines tolerated in patients with paclitaxel and docetaxel allergy

Banerji, A., Wolfson, A.R., Robinson, L.B., et al. Allergy. First published: 14 November 2021

Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways

Aliee, H., Massip, F., Qi, C., et al. Allergy. First published: 26 October 2021

The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine

Labella, M., Céspedes, J.A., Doña, I., et al. Allergy. First published: 24 October 2021

RBD-IgG levels correlate with protection in residents facing SARS-CoV-2 B.1.1.7 outbreaks

Blain, H., Tuaillon, E., Gamon, L., et al. Allergy. First published: 15 October 2021

Persistence of infectious SARS-CoV-2 particles for up to 37 days in patients with mild COVID-19

Zahn, T., Mhedhbi, I., Hein, S., et al. Allergy. First published: 12 October 2021

What we know and still ignore on COVID-19 immune pathogenesis and a proposal based on the experience of allergic disorders

Maggi, E, Azzarone, BG, Canonica, GW, Moretta, L. Allergy. First published: 28 September 2021

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet, J., Agache, I., Blain, H., et al. Allergy. 2021; 76: 2952-2964

Predictors of treatment response in chronic spontaneous urticaria

Fok, J.S., Kolkhir, P., Church, M.K. and Maurer, M. Allergy. 2021; 76: 2965-2981

Interleukin-31: The “itchy” cytokine in inflammation and therapy

Datsi, A., Steinhoff, M., Ahmad, F., Alam, M. and Buddenkotte, J. Allergy. 2021; 76: 2982-2997

Markers for the involvement of endothelial cells and the coagulation system in chronic urticaria: A systematic review

Mostmans, Y., De Smedt, K., Richert, B., et al. Allergy. 2021; 76: 2998-3016

Eczema herpeticum in atopic dermatitis

Traidl, S., Roesner, L., Zeitvogel, J. and Werfel, T. Allergy. 2021; 76: 3017-3027

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp, T, Acar Şahin, A, Aggelidis, X, et al. Allergy. 2021; 76: 3041– 3052

Direct assessment of individual skin barrier components by electrical impedance spectroscopy

Mannweiler, R., Bergmann, S., Vidal-y-Sy, S., Brandner, J.M. and Günzel, D. Allergy. 2021; 76: 3094-3106

Prenatal paraben exposure and atopic dermatitis-related outcomes among children

Thürmann, L, Herberth, G, Seiwert, B, et al. Allergy. 2021; 76: 3122– 3132

Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis

Kopfnagel, V, Dreyer, S, Zeitvogel, J, et al. Allergy. 2021; 76: 3145– 3154

Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy

Tesfaye, A., Rodríguez-Nogales, A., Benedé, S., et al. Allergy. 2021; 76: 3183-3193

Sweet syndrome induced by SARS-CoV-2 Pfizer-BioNTech mRNA vaccine

Darrigade, A.-S., Théophile, H., Sanchez-Pena, P., et al. Allergy. 2021; 76: 3194-3196

Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma

Lommatzsch, M., Klein, M., Stoll, P. and Virchow, J.C. Allergy. 2021; 76: 3199-3202

Identification of Ulocladium chartarum as an important indoor allergen source

Pfeiffer, S., Sandler, P., Raith, M., et al. Allergy. 2021; 76: 3202-3206

Effects of allergen immunotherapy in the MASK-air study: a proof-of-concept analysis

Pfaar, O., Sousa-Pinto, B., Devillier, P., et al. Allergy. 2021; 76: 3212-3214

Legends of allergy and immunology: Sergio Bonini

Maltese, G. and Rasi, G. Allergy. 2021; 76: 3227-3229

Medical algorithm: Peri-operative management of mastocytosis patients

Bocca-Tjeertes, I.F.A., van de Ven, A.A.J.M., Koppelman, G.H., et al. Allergy. 2021; 76: 3233-3235

Junior Members Corner



Dear Juniors,


Despite these challenging times, EAACI is keeping up with several scientific activities, aiming to being able to meet you all in person soon! The next upcoming appointments are:

- EAACI Pediatric Allergy and Asthma Meeting (PAAM) digital 2021:


It will take place on 12–13 November 2021, in an interactive hybrid format that will allow you to take part in scientific discussions both on-site both from the safety of your home through an innovative and highly interactive concept. The aim is to share new research and findings with internationally renowned experts in the common effort to come up with solutions to the most pressing challenges in the evolving pediatric field.

You can find any information about PAAM by clicking here



- 20th Immunology Winter School on Basic Immunology Research in Allergy and Clinical Immunology:


It will take place from 27 to 30 January 2022, in Semmering (Austria) in an interactive hybrid format. The event will gather 70 young researchers, PhD students and junior postdoc, active in the field of allergy, asthma, clinical immunology/immune deficiency with a focus on basic and/or clinical immunology. The participants will be selected on the basis of the quality of their submitted abstracts.

You can submit your abstract until the 7th of November by clicking here

We look forward to seeing you at our incoming activities and working together to ensure that the highest standards of care are implemented and shared within our specialty.

Best regards,
The Junior Member Assembly


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